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| 3.Keystone Symposia: Sirtuins in Metabolism, Aging and Disease |
| Dates | 12 Fév 2012 → 17 Fév 2012 | [ID=427757]  |
| Lieu | Tahoe City, CA, États-Unis |
| Résumé | Sirtuins comprise a unique class of NAD+-dependent enzymes that modify multiple protein substrates to execute diverse biological functions. Sirtuins are key regulators of clinically important cellular and organismal processes including metabolism, cell division and aging. The desire to understand the important determinants of human health and lifespan has resulted in a firestorm of work on the seven mammalian sirtuins in the past decade. The implication of sirtuins in medically important areas such as diabetes, cancer, cardiovascular dysfunction and neurodegenerative disease has catapulted them to a prominent status as potential targets for nutritional and therapeutic development. The Keystone Symposia meeting on Sirtuins in Metabolism, Aging and Disease will address fundamental questions on the regulation, biochemical, molecular and cellular mechanisms and pathways of sirtuins. The significance of sirtuin-dependent regulation of homeostasis with respect to diverse biological organisms will be discussed. We envision that this meeting will evaluate the relevance of sirtuin biology in various human conditions, and provide a unique environment for discussing specific therapeutic strategies. |
| Sujets | Cell Biology, Small Molecule Chemistry, Drug Discovery, Metabolic Diseases, Neurodegenerative Disease, Neurobiology, Cancer Prevention, Aging, Cell Biology, Keystone Symposia, Sirtuins, Metabolism |
| Page web | http://www.keystonesymposia.org/12B2 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 4.Keystone Symposia: G Protein-Coupled Receptors: Molecular Mechanisms and Novel Functional Insights |
| Dates | 17 Fév 2012 → 22 Fév 2012 | [ID=427819] |
| Lieu | Banff, Alberta, Canada |
| Résumé | The seven transmembrane-spanning G protein-coupled receptors (GPCRs) are the largest superfamily of receptors in the human genome, are involved in virtually all physiological processes and represent the targets for at least 30% of all current medicines. Recent years have witnessed the coalescing of a number of important paradigms, including ligand-biased signaling, allosteric modulation and receptor dimerization, with substantial advances in structural determination, chemical biology and in vivo approaches to studying GPCR function. These developments will undoubtedly have a profound impact on future approaches to GPCR-based drug discovery. This meeting will focus on the interplay between these developments, and how they can be exploited to advance the translational application of cutting-edge GPCR-based research. |
| Sujets | Keystone Symposia, G Protein-Coupled Receptors, Molecular Mechanisms, Novel Functional Insights, Signaling, Signalling, Biochemistry, Drug Discovery, Diagnostics |
| Page web | http://www.keystonesymposia.org/12B4 |
| Sujets apparentés | Pharmacologie et développement des médicaments; Médecine (en général) |
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| 5.Mastering Medicinal Chemistry Summit |
| Dates | 21 Fév 2012 → 23 Fév 2012 | [ID=445638] |
| Lieu | San Francisco, États-Unis |
| Page web | http://www.triconference.com/mch/ |
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| 6.Keystone Symposia: ApoE, Alzheimer's and Lipoprotein Biology |
| Dates | 26 Fév 2012 → 02 Mar 2012 | [ID=427817] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | Apolipoprotein E4 (ApoE4) genotype is the primary risk factor for late-onset Alzheimer?s Disease. Approximately one fifth of the human population are ApoE4 carriers, yet more than 17 years after its discovery, the molecular basis by which this common allele causes neurodegeneration is still not understood. One major reason is the lack of effective communication between lipid researchers who have investigated the role of ApoE as a plasma lipid transport protein, and neuroscientists who are unfamiliar with the complex biochemistry of lipid metabolism and the cell biology of ApoE receptors. This is confounded by the methodological difficulty of studying lipid metabolism and lipoprotein transport in the brain and the paucity of pioneering work tackling this problem. Yet, the solution to one of the most pressing socioeconomic problem of our times, the looming Alzheimer?s Disease epidemic, depends on our ability to dissect and understand the molecular mechanism by which ApoE4 is causing this disease. The purpose of this highly interdisciplinary meeting on ApoE, Alzheimer?s and lipoprotein biology is to bring together a critical mass of experts with complementary expertise from these different fields, but who do not normally collaborate or attend the same conferences. In this manner, we envisage this meeting serving as the main catalyst for communication and collaboration between lipid and lipoprotein researchers, neurogeneticists, cell biologists and synaptic neurophysiologists. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Clinical and Molecular Biology of Acute and Chronic Traumatic Encephalopathies, which will share opening keynote addresses and a fourth day of sessions with this meeting. |
| Sujets | Keystone Symposia, ApoE, Alzheimer's, Lipoprotein Biology, Neurodegenerative Disease, Neurobiology, Signaling, Signalling |
| Page web | http://www.keystonesymposia.org/12Q5 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 7.Keystone Symposia: Clinical and Molecular Biology of Acute and Chronic Traumatic Encephalopathies |
| Dates | 26 Fév 2012 → 02 Mar 2012 | [ID=427816] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | Acute traumatic brain injury (TBI) and its long-term neurodegenerative complications (known collectively as chronic traumatic encephalopathy, or CTE) are increasingly recognized as major public health issues, especially in the context of sports-related head injury and battlefield blast (military) exposure. Awareness of these issues has risen as neurological, psychiatric and neurodegenerative phenomena are associated with professional athletes and with veterans returning from Iraqi and Afghan theaters. The physics of head injury, as well as the epidemiological and neuropsychiatric aspects of sports-related and blast-related syndromes, will be reviewed in the initial sessions of this three-day meeting. Advances in functional neuroimaging and in the rapid and convenient determination of peptides and proteins in the cerebrospinal fluid and plasma will be reviewed in terms of their possible pathobiological significance as well as their identities as possible biomarkers. Later sessions will focus on the overlap between CTE and major neurodegenerative diseases, such as Alzheimer?s Disease (AD), frontotemporal dementia and amyotrophic lateral sclerosis. CTE is associated with accumulation of aggregated proteins or protein fragments, including tau, TDP-43, the Alzheimer?s amyloid precursor protein (APP) and the APP metabolite, amyloid-b. New experimental therapeutics research targets the roles these abnormal protein structures play in injury severity and subsequent outcome. Ab-lowering medications, currently in clinical trials for AD, improve outcome following acute brain trauma in rodent models, suggesting a pathway toward potential therapeutic interventions. Because apolipoprotein E (APOE) isotype is an important determinant of outcome from acute severe as well as mild repetitive TBI, this meeting coincides in time and venue with the Keystone Symposia meeting on ApoE, Alzheimer?s and Lipoprotein Biology. Opening plenary sessions and an optional fourth day of sessions are available for those interested in learning more about basic biology and/or clinical interventions related to APOE. |
| Sujets | Keystone Symposia, Clinical and Molecular Biology, Acute and Chronic Traumatic Encephalopathies, Neurobiology |
| Page web | http://www.keystonesymposia.org/12Q6 |
| Sujets apparentés | Neurologie; Médecine (en général) |
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| 8.Medicinal Chemistry Conference 2012 |
| Dates | 02 Mar 2012 → 05 Mar 2012 | [ID=435844] |
| Lieu | Lanzarote, Espagne |
| Organisateur | Zing Conferences |
| Page web | http://www.zingconferences.com/index.cfm?page=list&type=conference |
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| 9.Keystone Symposia: Protein-RNA Interactions in Biology and Disease |
| Dates | 04 Mar 2012 → 09 Mar 2012 | [ID=427782] |
| Lieu | Santa Fe, NM, États-Unis |
| Résumé | Cellular functions depend on numerous protein-coding and noncoding RNAs and the RNA-binding proteins (RBPs) associated with them, which form ribonucleoprotein complexes (RNPs). Mutations that disrupt either the RNA or protein components of RNPs or the factors required for their assembly can be deleterious. The discovery of disease-causing mutations in RNAs or their interacting RBPs not only adds to our growing understanding of RNA biology and chemistry, but also offers new therapeutic targets and contributes to ongoing efforts in developing mRNA-targeting antisense and RNAi therapeutics. This meeting focuses on a general understanding of post-transcriptional gene regulation and how perturbation of complex networks of RNA-protein and RNA-RNP interactions triggers disease. |
| Sujets | Keystone Symposia, Protein, Protein-RNA Interactions in Biology and Disease, Transcription, Translation, Expression, Molecular Biology, Signaling, Biochemistry, Cell Biology, Systems Biology, Genetics, Genomics, iRNA, Processing, Noncoding |
| Page web | http://www.keystonesymposia.org/12C1 |
| Sujets apparentés | Biologie moléculaire; Médecine (en général) |
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| 10.Keystone Symposia: Innate Immunity: Sensing the Microbes and Damage Signals |
| Dates | 04 Mar 2012 → 09 Mar 2012 | [ID=427825] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | In recent years there have been major advances in our understanding of the mechanisms that are involved in the recognition of microbes and subsequent activation of host immune defenses. Several classes of membrane-bound and cytosolic pattern recognition receptors (PRRs) have been identified and partially characterized. These include the Toll-like receptors (TLRs), NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs). Activation of PRRs leads to the production of a large array of pro-inflammatory and anti-microbial molecules that are critical for the elimination of invading pathogens and activation of adaptive immune responses. A class of cytosolic PRRs is involved in the assembly of the inflammasome, a molecular platform that mediates activation of caspase-1 and secretion of mature IL-1b and IL-18. Importantly, activation of the inflammasome is also induced by non-microbial mechanisms including endogenous molecules involved in the pathogenesis of metabolic and inflammatory diseases. In addition, there is evidence that autophagy, a cellular process that mediates recycling of intracellular components, is involved in microbial recognition and plays a key role in host defense. The initial sensing of microbes often occurs at mucosal surfaces, but the interplay between recognition of commensal vs. pathogenic microbes on the host immune system is only beginning to be uncovered. The goal of the Keystone Symposia meeting on Innate Immunity: Sensing the Microbes and Damage Signals is to gather scientists working on innate immunity to discuss cutting-edge research on the mechanisms that regulate the activation of the immune system by microbes as well as by endogenous damage signals, and to integrate such knowledge in the context of inflammation, homeostasis, host defense and disease. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on The Microbiome, which will share a keynote address and three plenary sessions with this meeting. |
| Sujets | Keystone Symposia, Innate Immunity, Sensing the Microbes and Damage Signals, Leukocytes, Immunology, Bacterial, Infectious Diseases, Viral, Signaling, Inflammation |
| Page web | http://www.keystonesymposia.org/12Q7 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 11.Keystone Symposia: The Microbiome |
| Dates | 04 Mar 2012 → 09 Mar 2012 | [ID=427868] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | Emerging themes from several traditionally disparate areas of research have begun to coalesce around the concept that the complex microbial communities that inhabit most external human surfaces play a key role in health and disease. Specifically, processes including basic immune system development, host-pathogen interactions, metabolic disease and cancer are all greatly influenced by the composition and bioactivity of the microbiota that live within us. Understanding how mammalian hosts regulate their microbiota and the myriad of ways by which the microbiota can alter susceptibility to a wide range of diseases is a key opportunity to better understand numerous diseases and, subsequently, provide strategies to promote human health. Thus, the goal of the Keystone Symposia meeting on The Microbiome is to facilitate the understanding of mechanisms that maintain a healthy host-microbiota relationship and explore how perturbations in this relationship increase susceptibility to a variety of diseases, especially those associated with chronic inflammation. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Innate Immunity: Sensing the Microbes and Damage Signals, which will share a keynote address and three plenary sessions with this meeting. |
| Sujets | Keystone Symposia, The Microbiome, Infectious Diesase |
| Page web | http://www.keystonesymposia.org/12Q8 |
| Sujets apparentés | Médecine (en général); Biologie |
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| 12.Keystone Symposia: Nuclear Events in Plant Gene Expression and Signaling |
| Dates | 06 Mar 2012 → 11 Mar 2012 | [ID=427845] |
| Lieu | Taos, NM, États-Unis |
| Résumé | The complete sequences of a number of plant genomes and the advent of high-throughput technologies have, in the past few years, fueled intensive research efforts to unravel the mechanisms underlying gene and genome regulation. It is clear that a host of epigenetic processes including, but not limited to, DNA methylation and various histone modifications, underlie key developmental processes as well as biotic and abiotic interactions. Non-coding RNAs have been increasingly recognized as players in gene expression and genome defense. Various types of subcellular bodies in the nucleus have been identified and associated with transcription factors, RNA processing proteins and epigenetic regulators. Despite these advances, a holistic view of gene and genome regulation at the DNA, RNA, protein, cell biological and developmental levels is still lacking. By bringing together researchers working on various aspects of genome dynamics and gene expression, this symposium on Nuclear Events in Plant Gene Expression and Signaling aims to stimulate the synthesis of an integrative view of nuclear dynamics in plant biology. |
| Sujets | Keystone Symposia, Nuclear Events in Plant Gene Expression and Signaling, Plant Biology |
| Page web | http://www.keystonesymposia.org/12C2 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 13.International Scientific Forum on CO2 Chemistry and Biochemistry |
| Dates | 07 Mar 2012 → 09 Mar 2012 | [ID=463970] |
| Lieu | Rennes, France |
| Sujets | Green processes and catalysis, Activation and functionalization of C-H bonds, Renewable raw materials and catalysis, Alkene/Alkyne metathesis, Asymmetric catalysis, Energy conversion and storage, Green chemistry in industry, Organometallics at the frontier of catalysis. |
| Page web | http://britgreencat.univ-rennes1.fr/index.html |
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| 14.Keystone Symposia: Regulation of Lymphocyte Signaling |
| Dates | 11 Mar 2012 → 16 Mar 2012 | [ID=427898] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | Key individual components of signaling pathways that control lymphocyte activation have been identified. However, their specific regulation, integration within pathways and regulation are still the subject of intense investigation. Currently, they are being probed through biochemical, chemical-genetic, modeling and imaging methods. Major hurdles still reflect our very simplistic understanding of both the kinetic parameters of the molecules involved as well as the complexity of the regulatory circuits of these signaling pathways. Moreover, it is still quite difficult to translate such information into downstream biologically important information. The fact that therapeutics targeting these signaling pathways are still lagging is not surprising. The Keystone Symposia meeting on Regulation of Lymphocyte Signaling will highlight different methodologies and approaches aimed at developing a better integration of complex information about signaling. This information will lead to better understanding of how the normal immune system functions and where interventions in signaling pathways can be used in diseases of the immune system. |
| Sujets | Keystone Symposia, Regulation of Lymphocyte Signaling, Immunology |
| Page web | http://www.keystonesymposia.org/12C4 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 15.Keystone Symposia: Mutations, Malignancy and Memory ? Antibodies and Immunity |
| Dates | 18 Mar 2012 → 22 Mar 2012 | [ID=427929] |
| Lieu | Boston, MA, États-Unis |
| Résumé | Mutations in the human genome are regarded as potentially disastrous events that lead to carcinogenesis. From the vantage point of B cell immunology, however, programmed DNA alterations at the antibody gene loci are essential for efficient antibody responses. A plethora of recent findings are beginning to illuminate open questions about the precise molecular mechanisms of these diversification processes, their regulation, and how errors in these pathways lead to cancer. Furthermore, the very same class of mutator enzymes plays an underappreciated role in non-lymphoid cancers, in antiviral responses and in epigenetic reprogramming. Antibody diversification not only shapes the repertoires of the immunological memory, but also those of auto-antibodies. The Keystone Symposia meeting on Mutations, Malignancy and Memory ? Antibodies and Immunity will provide both a platform to integrate these more or less isolated fields and an opportunity to identify interfaces that could be relevant for therapeutic approaches in malignancies and autoimmune diseases. |
| Sujets | Keystone Symposia, Mutations, Malignancy, Memory, Antibodies, Immunity, Cancer, B-Cell Biology, B Cell |
| Page web | http://www.keystonesymposia.org/12C6 |
| Sujets apparentés | Médecine (en général) |
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| 16.Keystone Symposia: NF-kappaB Signaling and Biology: From Bench to Bedside |
| Dates | 18 Mar 2012 → 23 Mar 2012 | [ID=427840] |
| Lieu | Whistler, BC, Canada |
| Résumé | The regulation and function of NF-kB have captivated molecular and cellular biologists, as well as immunologists, pathologists and drug developers for many years. Studies of NF-kB and its regulation have taught us many fundamental lessons and principals in basic biological sciences as well as in biomedicine. Although rapidly reaching maturity, with 25 years since its discovery, the NF-kB field remains vibrant and fertile, and never ceases to amaze with new groundbreaking discoveries. The Keystone Symposia meeting on NF-kB Signaling and Biology: From Bench to Bedside will cover the basic biochemistry of NF-kB signaling; how NF-kkB accomplishes its main job as a transcription factor; the roles of the NF-kB system in immunity and inflammation; how NF-kB controls cell death, survival and metabolism; and how all of these functions go awry during disease development ? something that we have learned both from studies of genetically altered mice and from studies of human genetic defects and pathology. Finally, this meeting will teach us how we might fix and cure these problems through the pharmacological targeting of the NF-kB system. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Ubiquitin Signaling, which will share a keynote address and three plenary sessions with this meeting. |
| Sujets | Keystone Symposia, NF-êB, NF-kappaB, Signaling, Biology, Biochemistry, newly identified cofactors in linking different signaling pathways |
| Page web | http://www.keystonesymposia.org/12X1 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 17.Keystone Symposia: Ubiquitin Signaling |
| Dates | 18 Mar 2012 → 23 Mar 2012 | [ID=427916] |
| Lieu | Whistler, BC, Canada |
| Résumé | Post-translational modifications of cellular proteins by ubiquitin and ubiquitin-like modifiers regulate a variety of functions in the cell. A crucial aspect of signaling through ubiquitin and Ubls is the presence of modular binding domains that recognize particular types of ubiquitin signals. Such molecular coupling creates an attractive ?decoding? mechanism for responding to alterations in the cellular microenvironment and regulating physiological and pathophysiological conditions. In this meeting, we will discuss the major challenges in the field including detection of endogenous ubiquitination events, functional aspects of novel types of ubiquitin chains and their recognition by selective binding domains, and high-throughput technologies for comprehensive analysis of Ub modifications. The intersection between the deregulated ubiquitin signaling, pathogenesis of human diseases and therapies targeting the Ub system will be explored. The program offers a possibility for young scientists to present their own work and engage in discussions on the emerging topics in the field. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on NF-kB Signaling and Biology: From Bench to Bedside, which will share a keynote address and three plenary sessions with this meeting. |
| Sujets | Signaling, Inflammation, Immunology, Biochemistry, Keystone Symposia, Ubiquitin Signaling, NF-kappaB, NF-kB, Whistler, British Columbia, Canada |
| Page web | http://www.keystonesymposia.org/12X2 |
| Sujets apparentés | Médecine (en général); Biologie |
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| 18.Society for Endocrinology: BES 2012 |
| Dates | 19 Mar 2012 → 22 Mar 2012 | [ID=434511] |
| Lieu | Harrogate, Royaume-Uni |
| Résumé | We are delighted to bring the Society for Endocrinology BES back to Harrogate for 2012. Many of us are already familiar with the excellent congress centre and the lovely town and I?m sure we all look forward to sampling Yorkshire?s finest afternoon tea at ?Betty?s tea shop?. Try not to stay there for too long though as you might miss some of the best of British and International basic science and translational research, clinical investigation and clinical practice in endocrinology. Please see the scientific programme for full details of the exciting programme we have lined up for you in 2012. |
| Page web | http://www.endocrinology.org/meetings/2012/sfebes2012/ |
| Sujets apparentés | Biologie moléculaire; Médecine (en général) |
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| 19.Keystone Symposia: Addressing the Challenges of Drug Discovery ? Novel Targets, New Chemical Space and Emerging Approaches |
| Dates | 19 Mar 2012 → 23 Mar 2012 | [ID=427915] |
| Lieu | Tahoe City, CA, États-Unis |
| Résumé | The scientific and organizational landscape that underpins drug discovery is in a state of rapid evolution. The cellular signal transduction processes and biochemical pathways that enable life are increasingly understood at the molecular level and hypotheses for disease intervention can be proposed within this rational context. Technology to enable discovery of ligands to perturb the function of biological targets continues to advance and new methods to create small molecule tools to interrogate biological processes and potentially serve as drug leads are under development. However, while industry investment in R&D has grown exponentially, approval of new medicines has remained constant for several decades. Juxtaposition of this scientific opportunity, the continuing societal need for new drugs, and a failing model for translation of basic research into new medicines provides fertile soil for new ideas and approaches.
This meeting will focus on addressing these challenges in drug discovery with an emphasis on novel biological targets, new chemical space and emerging organizational approaches to more effective translation. The goals of the meeting are:
? To explore relatively uncharted protein target class families to define new druggable biological space
? To survey promising new chemical approaches for ligand discovery
? To highlight new organizational constructs for drug discovery with an emphasis on public/private partnerships
The meeting aims to bring together medicinal chemists, disease biologists, chemical biologists, assay developers, and screeners from industry and academics, along with leaders of R&D organizations to create a dynamic exchange around the challenges facing drug discovery. |
| Sujets | Keystone Symposia, Challenges, Drug Discovery, Novel Targets, New Chemical Space, Emerging Approaches, Diagnostics |
| Page web | http://www.keystonesymposia.org/12F1 |
| Sujets apparentés | Pharmacologie et développement des médicaments; Médecine (en général) |
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| 20.Keystone Symposia: Cell Death Pathways: Beyond Apoptosis |
| Dates | 19 Mar 2012 → 24 Mar 2012 | [ID=427913] |
| Lieu | Banff, AB, Canada |
| Résumé | Mounting evidence indicates that cell death in diseases results from complex interactions between molecular mechanisms taking place within the degenerating cells (cell-autonomous) and outside the degenerating cells (non-cell autonomous). At the cross roads of these diverse signaling pathways are found the mitochondria which, through proper mitochondrial dynamics and regulated mitochondrial elimination by autophagy (i.e., mitophagy), play a crucial role in maintaining the well-being of the cells. This meeting will focus on the general mechanisms of cell death including the Bcl-2 family and caspase proteases, the role of mitochondrial dynamics and mitophagy, the usefulness of bioinformatics to unravel death-pathways, the contribution of non-cell autonomous mechanisms to cell death and the therapeutic strategies to protect against cell death. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Mitochondrial Dynamics and Function, which will share a keynote address and two plenary sessions with this meeting. |
| Sujets | Keystone Symposia, Cell Death Pathways, Apoptosis, pathogenesis, tumor, immunology, Neurodegenerative Disease, Neurobiology, Signaling, Biochemistry, Basic mechanisms, cancer |
| Page web | http://www.keystonesymposia.org/12X4 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 21.RSC-BMCS CBDD — 2nd RSC symposium on Chemical Biology for Drug Discovery |
| Dates | 20 Mar 2012 → 21 Mar 2012 | [ID=463246] |
| Lieu | Macclesfield, Royaume-Uni |
| Résumé | This symposium covers progress in the interdisciplinary field of Chemical Biology in enhancing our understanding of the molecular mechanisms of human biology in health and disease. Topics will include discovery and use of chemical probes, chemical modification of biological molecules, in-cell protein labelling, carbohydrate therapeutics and biomarkers, and the study of protein-protein interactions. |
| Sujets | Chemical Biology, Drug Discovery, Target,Discovery, Carbohydrates, Activity-Based Protein ProfilingmIn-cell Protein, Labelling, Protein-Protein Interactions, Epigenetics, Kinases, Stem cells,Chemical Probes, Medicinal Chemistry |
| Page web | http://www.maggichurchouseevents.co.uk/bmcs |
| Contact | Mrs Maggi Churchouse RSC-BMCS Secretariat Maggi Churchouse Events 3 East Barn Market Weston Road Thelnetham Diss IP22 1JJ UK; Tél.: [+44 (0)1359 221004]; Email.: maggi@maggichurchouseevents.co.uk |
| Sujets apparentés | Foire exposition chimie; Pharmacologie et développement des médicaments |
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| 22.EURO Bio-inspired Materials |
| Dates | 20 Mar 2012 → 23 Mar 2012 | [ID=456970] |
| Lieu | Potsdam, Allemagne |
| Page web | http://www.dgm.de/bio-inspired |
| Sujets apparentés | Métallurgie et science des matériaux |
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| 23.Keystone Symposia: HIV Vaccines |
| Dates | 21 Mar 2012 → 26 Mar 2012 | [ID=427934] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | The 2012 Keystone Symposia meeting on HIV Vaccines will focus on basic aspects of immunology and HIV-1 virology to highlight issues that challenge the field. The genetic diversity of circulating HIV-1 variants puts extreme demands on the quality of the response a prophylactic vaccine will need to elicit. Most likely, conserved viral determinants need to be targeted and the response must be sustained over time. To facilitate a broad and open discussion around these topics, the symposium will convene expert investigators from the HIV-1 vaccine field as well as a number of basic immunologists. Aspects of natural HIV-1 infection of direct relevance to the development of a vaccine, such as viral transmission and viral escape from immune responses, will be addressed in joint sessions with the parallel meeting on Viral Immunity and Host Gene Influence. Speakers will also be invited to present in the workshops and in the oral sessions based on submitted abstracts. |
| Sujets | Keystone Symposia, HIV, vaccines, immunology, infectious diseases, viral, cell, biology, b-cell, t-cell |
| Page web | http://www.keystonesymposia.org/12X5 |
| Sujets apparentés | Médecine (en général); Biologie |
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| 24.Keystone Symposia: Viral Immunity and Host Gene Influence |
| Dates | 21 Mar 2012 → 26 Mar 2012 | [ID=427955] |
| Lieu | Keystone, CO, États-Unis |
| Résumé | This meeting will focus on recent advances in viral immunity and host gene influence that have most excited the scientific community. Systems biology approaches are being increasingly applied to the exploration of host-pathogen interactions, including the impact of viral infection on innate and adaptive immunity. Accordingly, the keynote talk will be on this topic. The first full session on the next day will focus on innate immunity, a field that continues to evolve rapidly and hold great interest in the field. In the evening the audience will hear from others who have successfully applied a systems biology approach to examine virus-host interactions. The second day explores adaptive immunity, a topic that historically has been a centerpiece for this meeting, and an area that continues to move forward rapidly. On the third day, the morning session will focus on immune evasion and subversion and will illustrate how formidable the opposition can be and why vaccine development for a number of important human diseases is so challenging. Talks on persistent and chronic viral infections, a topic with clear relevance to a number of human diseases, will be covered in the evening session. The morning session of the final day will cover immune tailoring in non-lymphoid tissues; talks will illustrate how different host responses can and must be, depending upon anatomical location of the infection. The final session will cover the latest advances in the development of vaccines and therapeutics, the traditional ending for this meeting series and a reminder to attendees of the ultimate objectives.
Overall, the objective of the Keystone Symposia meeting on Viral Immunity and Host Gene Influence is to accelerate progress in understanding and manipulating anti-viral immunity to improve human health. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on HIV Vaccines, which will share a keynote address and three plenary sessions with this meeting. We anticipate this pairing will facilitate a wider cross-fertilization of ideas and foster innovative collaborations among scientists working in vaccinology and those studying innate immune mechanisms and other viral diseases. |
| Sujets | Keystone Symposia, Viral, Immunity, Host, Gene, Influence, immune mechanisms, immunology, infectious diseases, systems, biology, cell, antibodies, innate, immunity, t-cell, |
| Page web | http://www.keystonesymposia.org/12X6 |
| Sujets apparentés | Médecine (en général); Biologie |
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| 25.Biochemical Journal - US Symposium |
| Date de début | 22 Mar 2012 | [ID=448075] |
| Lieu | La Jolla, CA, États-Unis |
| Résumé | In gratitude to the Sanford-Burnham Medical Research Institute for hosting its US Editorial Office, the Biochemical Journal is sponsoring a special one-day symposium on Thursday March 22nd 2012. Registration for this event is free. |
| Page web | http://www.biochemj.org/bj/symposium/ |
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| 26.Intrinsically disordered proteins |
| Dates | 26 Mar 2012 → 27 Mar 2012 | [ID=433366] |
| Lieu | York, Royaume-Uni |
| Page web | http://www.biochemistry.org/MeetingNo/SA128/view/Conference/ |
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| 27.Keystone Symposia: Cell Biology of Virus Entry, Replication and Pathogenesis |
| Dates | 26 Mar 2012 → 31 Mar 2012 | [ID=427930] |
| Lieu | Whistler, BC, Canada |
| Résumé | This meeting will highlight recent advances in virus infection pathways, and in the cellular responses to viral infection. The meeting features multiple stages of the viral lifecycle analyzed using a broad array of techniques and levels of analysis. A novel feature of this meeting is that it will be held concurrently with the Keystone Symposia meeting on Frontiers in HIV Pathogenesis, Therapy and Eradication and will, therefore, focus on maximizing exchange between the HIV community and the broader community of virologists. An explicit goal is to bring together and promote potential synergies among researchers who might not otherwise interact in more specialized meetings. A classic, almost paradigmatic, example of the power of this cross-talk is the contribution of studies of influenza A virus hemagglutinin to our understanding of the HIV-1 entry process, and the subsequent contribution of both systems to our understanding of type I fusion, type II fusion and the entry processes of non-enveloped viruses. Accordingly, two common sessions will focus on the retroviral entry process and its inhibition, followed by talks featuring a broader survey of viral entry, replication, structural and systems approaches to virology, host immune evasion and therapeutics. |
| Sujets | Keystone Symposia, Cell, Biology, Virus, Entry, Replication, Pathogenesis, virologists, viral, infectious diseases, membrane, proteins, antibodies, innate, immunity, biochemistry |
| Page web | http://www.keystonesymposia.org/12X7 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 28.Keystone Symposia: Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics |
| Dates | 30 Mar 2012 → 04 Avr 2012 | [ID=427983] |
| Lieu | Big Sky, MT, États-Unis |
| Résumé | Fibrosis is a pathological process in which diseased tissue is replaced with excess extracellular matrix ultimately leading to organ scarring and failure, a final common pathway in many forms of chronic disease affecting multiple tissues. Currently, there are minimal and inadequate treatment options for fibrotic disease. The field of fibrosis is emerging and there is a strong need to understand the cellular, molecular and genetic basis of fibrosis in humans and to develop animal models that reproduce and dissect this pathological process. There is also a need to identify prognostic markers of disease susceptibility, biomarkers of disease progression and improved technologies to monitor the effectiveness of new therapies. The goal of the Keystone Symposia meeting on Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics is to bring together researchers and clinicians in academia and industry to provide an integrated perspective of basic disease mechanisms, the more pragmatic challenges associated with executing clinical trials and approaches to improve clinical development of anti-fibrotic drugs. |
| Sujets | Fibrosis, Disease, Novel, Therapeutics, Keystone Symposia, inflammation, immunity, innate, immunology, signaling, biochemistry, basic mechanisms, cancer, endothelium, cell, biology |
| Page web | http://www.keystonesymposia.org/12D1 |
| Sujets apparentés | Médecine (en général); Biologie |
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| 29.Keystone Symposia: Non-Coding RNAs |
| Dates | 31 Mar 2012 → 05 Avr 2012 | [ID=427982] |
| Lieu | Snowbird, UT, États-Unis |
| Résumé | It has become apparent that RNA plays a major, but still largely unexplored, role in the regulation of gene expression. It is becoming increasingly evident that longer forms of non-protein-coding RNAs (ncRNAs) are involved directly in regulating gene expression and epigenetic states. These long ncRNAs appear to be functioning as an endogenous RNA regulatory system, playing a major role in the epigenetic control of differentiation and development. These observations, across various model systems, strongly suggest that long ncRNAs are more intricately involved in the regulation of gene expression than previously envisioned. The goal of the Keystone Symposia meeting on Non-Coding RNAs is to highlight the similarities and differences in various model systems to better understand the role of long ncRNAs in the regulation of genomes. This is an entirely new emerging field of study that is on the forefront of modern biology. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Eukaryotic Transcription, which will share a plenary session with this meeting. |
| Sujets | Keystone Symposia, Non-Coding, RNAs, RNA, genetics, genomics, molecular, biology, transcription, translation, expression, vertebrate, development, chromatin, structure, function, processing, noncoding |
| Page web | http://www.keystonesymposia.org/12Z1 |
| Sujets apparentés | Biologie moléculaire; Médecine (en général) |
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| 30.Keystone Symposia: Synapses and Circuits: From Formation to Disease |
| Dates | 01 Avr 2012 → 06 Avr 2012 | [ID=427991] |
| Lieu | Steamboat Springs, CO, États-Unis |
| Résumé | A fundamental goal of neuroscience is to understand the molecular, cellular and activity-based mechanisms that control the formation and maintenance of neural circuits and determine how these mechanisms become compromised in neurodevelopmental, psychiatric and neurodegenerative disorders. Over the past two decades, molecular neuroscientists have identified key molecules and mechanisms that underlie synapse development, activity and stability. Meanwhile, the study of neuronal circuits has been revolutionized by new methods to visualize and map circuits in living animals, as well as the development of approaches to control neuronal activity using optical approaches (so called optogenetics). Finally, disease researchers have identified genes associated with neurodevelopmental and psychiatric disorders and neurodegenerative diseases. Animal models of these diseases are proving useful to understand how dysfunction of affected genes and proteins contributes to disease pathology. Although these fields are working on the same processes, no small highly interactive meeting brings these three groups together. The Keystone Symposia meeting on Synapses and Circuits: From Formation to Disease will address this need by bringing together leaders working on synapse development and function, circuit structure and function and the study of brain disease. We anticipate that mutually beneficial insights will emerge from discussions at this meeting. |
| Sujets | neural, circuits, neurodevelopmental, psychiatric, neurodegenerative, disorders, disease, development, neurobiology, neurophysiology, signaling, Keystone Symposia, synapses, circuits |
| Page web | http://www.keystonesymposia.org/12D2 |
| Sujets apparentés | Médecine (en général) |
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| 31.Keystone Symposia: Regenerative Tissue Engineering and Transplantation |
| Dates | 01 Avr 2012 → 06 Avr 2012 | [ID=428001] |
| Lieu | Breckenridge, CO, États-Unis |
| Résumé | Tissue engineering and regenerative medicine is a dynamic, translational research field that amalgamates life sciences, engineering and clinical medicine for the purpose of restoring structure and function to diseased, damaged or injured tissues and organs. Current efforts focus on the application of stem and progenitor cells, bioactive factors and biomaterial scaffolds in transplantation procedures to affect regenerative therapies. Breakthroughs in bladder and tracheal reconstruction and highly promising approaches for solid organ regeneration as well as musculoskeletal and nerve repair have been achieved. Effective cell sourcing, optimal assembly and fabrication of tissue-derived and synthetic biomaterial scaffolds, and targeted regulation of therapeutic and immunomodulatory functions of stem cells represent some of the current challenges in this field. In this Keystone Symposia meeting on Regenerative Tissue Engineering and Transplantation, exciting technological and intellectual advances in the field will be synthesized by expert scientists, engineers and clinicians to assess and expand the landscape in regenerative engineering and transplantation. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Mechanisms of Whole Organ Regeneration, which will share an opening and closing keynote address as well as two plenary sessions with this meeting. More specifically, the pairing of these two meetings represents a highly unusual opportunity for cross-talk between the more applications-driven field of tissue engineering and regenerative medicine, and the very basic research being explored in the field of whole organ regeneration. |
| Sujets | Keystone Symposia, Regenerative, Tissue, Engineering, Transplantation, organ systems, development, regenerative, technologies, transplantation |
| Page web | http://www.keystonesymposia.org/12Z3 |
| Sujets apparentés | Médecine (en général) |
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| 32.Keystone Symposia: Mechanisms of Whole Organ Regeneration |
| Dates | 01 Avr 2012 → 06 Avr 2012 | [ID=428099] |
| Lieu | Breckenridge, CO, États-Unis |
| Résumé | The regeneration of organs and organ systems after injury is widely, but unevenly, distributed among animals. Why organ regeneration is not shared by all animals, and whether mechanisms may or may not be conserved among those animals that can regenerate remain open questions. In recent years, the use of a wider range of model organisms and an increasing ability to use genetic tools to study regeneration has spurred significant progress in our understanding of animal regenerative biology. This meeting aims to delineate the molecular and cellular biological basis of regeneration by highlighting, comparing and contrasting the differences and similarities in regenerative capabilities and mechanisms among diverse animal species. How these biological findings may inform regenerative medicine and stem-cell biology and therapeutics will be considered and discussed. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Regenerative Tissue Engineering and Transplantation, which will share an opening and closing keynote address as well as two plenary sessions with this meeting. |
| Sujets | Keystone Symposia, Mechanisms, Organ, Regeneration, development, stem cells, genomics, systems, genetics, aging, cell, biology, morphogenesis |
| Page web | http://www.keystonesymposia.org/12Z4 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 33.Keystone Symposia: Nuclear Receptor Matrix: Reloaded |
| Dates | 15 Avr 2012 → 20 Avr 2012 | [ID=428032] |
| Lieu | Whistler, BC, Canada |
| Résumé | Nuclear receptors (NRs) represent a large superfamily of transcription factors that function as ligand-dependent sensors for a diverse set of fat-soluble hormones, vitamins and dietary lipids. Together, NRs govern expression of genes involved in a broad range of reproductive, developmental, metabolic and immune response programs. For this reason, NRs have been investigated for over 20 years as promising targets for drugs to treat a multitude of therapeutic indices, including cancer, diabetes, obesity, cardiovascular disease, hypertension, inflammation and cholestasis. However, despite the success of numerous NR-based therapies, there remain significant hurdles exploiting NRs to develop newer classes of therapies that achieve targeted benefits with reduced side effects. Thus, understanding the mechanisms, transcriptional targets and networks of physiologic pathways that govern NR action has become an important new strategy for evaluating the role of NRs in health and disease. This ?reloaded? effort is now beginning to produce exciting new avenues of research in the field. This meeting will bring together a key group of junior and senior investigators that are exploring these new directions and provide participants with a matrix of unique possibilities for them to investigate in both academic and pharmaceutical laboratory settings. |
| Sujets | Keystone Symposia, Nuclear, Receptor, Matrix, nucleus, cell, biology |
| Page web | http://www.keystonesymposia.org/12D3 |
| Sujets apparentés | Biologie; Biologie moléculaire |
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| 34.1st Israeli-UK Medicinal Chemistry Conference |
| Dates | 22 Avr 2012 → 23 Avr 2012 | [ID=463973] |
| Lieu | Rehovot, Israël |
| Page web | http://www.iamc.chemistry.org.il/ |
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| 35.Hatfield MedChem Meeting — 23rd symposium on Medicinal Chemistry in Eastern England |
| Date de début | 26 Avr 2012 | [ID=463289] |
| Lieu | Hatfield, Royaume-Uni |
| Résumé | A highly successful, long-standing, one-day meeting which runs annually. Traditionally the meeting has been held at the Fielder Centre in Hatfield, but will be hosted at the Eisai site, also in Hatfield, for the first time this year. The symposium, known colloquially as the "Hatfield MedChem" meeting, will comprise nine presentations which will cover various aspects of drug discovery, including medicinal chemistry case studies and SBDD, as well as more general topics related to medicinal chemistry and drug discovery. The meeting is applicable to all those working in medicinal chemistry and drug discovery and will also include the Capps-Green-Zomaya award presentation and lecture. In addition the meeting offers excellent networking opportunities. |
| Sujets | Capps Green Zomaya, East of England, Med chem, Hatfield, Hatfield medicinal chemistry, Hatfield meeting, medicinal chemistry, drug discovery |
| Page web | http://www.maggichurchouseevents.co.uk/bmcs |
| Contact | Mrs Maggi Churchouse RSC-BMCS Secretariat Maggi Churchouse Events 3 East Barn Market Weston Road Thelnetham Diss IP22 1JJ UK; Tél.: [+44 (0)1359 221004]; Email.: maggi@maggichurchouseevents.co.uk |
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| 36.Association for Clinical Biochemistry 2012 |
| Dates | 30 Avr 2012 → 03 Mai 2012 | [ID=445288] |
| Lieu | Liverpool, Royaume-Uni |
| Page web | http://www.acb.org.uk/docs/focus-2012-A5-leaflet-v1b.pdf |
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| 37.Ninth International 'RNAi: MicroRNAs & Oligos-Boston-2012 Meeting' On 'RNA interference & MicroRNAs: Biochemistry to Drugs & Therapeutics |
| Dates | 01 Mai 2012 → 02 Mai 2012 | [ID=462161] |
| Lieu | Waltham, États-Unis |
| Sujets | The Genetics of RNAi and microRNAs, RNAi, Oligos delivery in vivo, in vitro, microRNAs and their diverse roles in biology & disease, Computational and Disease Biology of miRNAs, Chemical synthesis of peptides and oligos, Large scale manufacturing and process development, Drug Target identification and Validation, High throughput genome-wide screenings, Development of Oligos and Peptide as Therapeuti, Clinical Application of Oligos and Peptides |
| Page web | http://www.expressgenes.com |
| Contact | Tél.: [7818918181]; Email.: sham@expressgenes.com |
| Sujets apparentés | Biologie |
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| 38.Third International 'Frontiers in Synthetic Biology, Biofuels & Green Chemistry-2012- Meeting' On 'Synthetic Genomes to Biofuels & Renewable Clean Energy Production' |
| Dates | 01 Mai 2012 → 02 Mai 2012 | [ID=462202] |
| Lieu | Waltham, États-Unis |
| Sujets | Synthetic Genomics & Organelle Synthesis, |
| Page web | http://www.expressgenes.com |
| Contact | PO Box 540179 Waltham, MA 02451 USA; Tél.: [7818918181]; Email.: sham@expressgenes.com |
| Sujets apparentés | Biotechnologie |
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| 39.ICE-ECE 2012 - 15th International and 14th European Congress of Endocrinology |
| Dates | 05 Mai 2012 → 09 Mai 2012 | [ID=434491] |
| Lieu | Florence, Italie |
| Page web | http://www.ice-ece2012.com/default.aspx |
| Sujets apparentés | Biologie moléculaire; Médecine (en général) |
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| 40.LIPID MAPS Meeting 2012 — LIPID MAPS Annual Meeting 2012: Impact on Cell Biology, Metabolomics and Translational Medicine |
| Dates | 07 Mai 2012 → 08 Mai 2012 | [ID=444296] |
| Lieu | La Jolla, California, États-Unis |
| Résumé | This is an exciting time for the emerging field of lipidomics. With the development and evolution of sophisticated mass spectrometers linked to highly efficient liquid chromatography systems, individual molecular species of lipids can now be isolated and identified, allowing us to begin to understand lipid metabolism and the treatment of lipid-based diseases (atherosclerosis and inflammatory disease as well as arthritis, cancer, diabetes and Alzheimer's disease). Recent awareness that each category of lipid consists of thousands if not tens of thousands of individual molecular species requires sophisticated informatics to ensure consistent databasing and annotation of the numerous lipid molecular species and analysis of tremendous quantities of experimental data. The goal of this meeting is to bring together biological and biomedical scientists in a wide range of fields to share new findings and methods in the broader lipidomics field and to explore joint efforts to extend the use of these powerful new methods to new applications. Presentations will provide an excellent introduction for scientists new to these methods, and are sure to be of interest to lipidomics veterans to learn about latest techniques and research results. |
| Sujets | Cancer, Inflammation, Macrophage Biology, Metabolic Disease, Metabolomics, Translational Medicine |
| Page web | http://www.lipidmaps.org/meetings/2012annual/index.html |
| Contact | Tél.: (858-822-5853); Email.: mdisenhouse@ucsd.edu |
| Sujets apparentés | Bio-informatique; Spectroscopie de masse et résonance magnétique nucléaire |
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| 41.Keystone Symposia: Proteomics, Interactomes |
| Dates | 07 Mai 2012 → 12 Mai 2012 | [ID=428020] |
| Lieu | Stockholm, Suède |
| Résumé | Discussion will focus on exploration of protein complexes, protein interactions with lipids and metabolites, the interplay with genomics, implications for cell signaling, and proteomics of ubiquitin and ubiquitin-like modifications. |
| Sujets | Keystone Symposia, Proteomics, Interactomes, biochemistry, lipids, metabolites, genomics, cell, signaling, ubiquitin, ubiquitin-like |
| Page web | http://www.keystonesymposia.org/12F2 |
| Sujets apparentés | Biologie; Médecine (en général) |
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| 42.Keystone Symposia: Drug Resistance and Persistence in Tuberculosis |
| Dates | 13 Mai 2012 → 18 Mai 2012 | [ID=428074] |
| Lieu | Kampala, Ouganda |
| Résumé | According to the World Health Organization, over 25% of new tuberculosis cases in some subnational regions are multi-drug-resistant TB (MDR-TB) and, as of March 2010, 58 countries had reported XDR-TB (TB resistant to the major classes of both first- and second-line drugs). The Keystone Symposia meeting on Drug Resistance and Persistence in Tuberculosis aims to bring together basic and clinical researchers and public health experts from diverse backgrounds to explore the following: 1) the fundamental biology underlying genetic and phenotypic drug-resistance in TB; 2) progress in expanding capacity in high-burden settings to perform drug susceptibility testing; 3) identification of novel drug targets; 4) innovative strategies for drug discovery; and 5) advances in developing multi-drug regimens that will be effective against currently drug-resistant as well as drug-sensitive strains of M. tuberculosis. Investigators from outside the TB field will be included to provide new perspectives and stimulate fresh approaches for tackling this global public health priority. |
| Sujets | Keystone Symposia, Drug, Resistance, Persistence, Tuberculosis, TB, bacterial, infectious, disease, drug discovery, diagnostics, high-throughput, small, molecule, chemistry |
| Page web | http://www.keystonesymposia.org/12E1 |
| Sujets apparentés | Pharmacologie et développement des médicaments; Médecine (en général) |
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| 43.NMCS — ACS 2012 National Medicinal Chemistry Symposium |
| Dates | 20 Mai 2012 → 23 Mai 2012 | [ID=461891] |
| Lieu | Tucson, États-Unis |
| Résumé | The 33rd National Medicinal Chemistry Symposium will be held from May 20-23rd, 2012 at the Hilton El Conquistador Resort in Oro Valley, AZ. Participants will represent both industry and academia and will include scientists ranging from graduate students to the most accomplished leaders in the field. We hope that you can join us in May 2012 for this exciting program at the grand El Conquistador Resort. |
| Sujets | medicinal chemistry, natural products, anti-infectives, neurodegeneration, chromatin, autoimmune, inflammatory, allosteric modulators, molecular libraries, graduate student, career development workshop |
| Page web | http://medchemconf.pharmacy.arizona.edu/index.html |
| Contact | Nicole Schechter 1580 East Hanley Blvd Oro Valley, AZ 85737; Tél.: [5206268222]; Email.: schechter@pharmacy.arizona.edu |
| Sujets apparentés | Chimie analytique; Foire exposition chimie |
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| 44.Keystone Symposia: The Role of Inflammation during Carcinogenesis |
| Dates | 20 Mai 2012 → 25 Mai 2012 | [ID=428139] |
| Lieu | Dublin, Irlande |
| Résumé | There is a growing appreciation that inflammation is the root cause of many cancers. Epidemiological and infectious disease literature supports this hypothesis. In addition, there is a growing body of experimental support confirming the role of inflammation in cancer initiation. However, once tumors are established, this inflammatory response changes and a set of immune cells are recruited that are immunomodulatory and not inflammatory. These types of immune cells, particularly those of the innate system, are also recruited to tumors in which there is no evidence for inflammation as a cause of tumorigenesis. This phenomenon has sometimes been called sterile inflammation. These immune cells enhance tumor progression and metastasis by promoting angiogenesis, enhancing tumor cell migration, invasion and intravasation and suppressing anti-tumor immunity. The conference will address the mechanisms behind the recruitment of the immune cells and their function, the switches in type of inflammatory responses during tumor progression and the actions of these cells in tumor promotion both at the primary and metastatic sites. |
| Sujets | Keystone Symposia, Inflammation, Carcinogenesis, basic, mechanisms, cancer, clinical, translational, prevention, infectious, diseases, technology, imaging |
| Page web | http://www.keystonesymposia.org/12E2 |
| Sujets apparentés | Biologie; Cancérologie |
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| 45.Biopolymers |
| Dates | 03 Jui 2012 → 08 Jui 2012 | [ID=454796] |
| Lieu | Newport, RI, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | The 2012 Biopolymers Gordon Research Conference will explore recent advances and future trends in understanding the relationship between structure and function of biological polymers (e.g. proteins, nucleic acids, macromolecular assemblies), with emphasis on physical and chemical principles underlying their behaviors in solution and in the cellular environment. Session topics will span multiple disciplines, including the consequences of macromolecular crowding, the mechanisms of macromolecular complex assembly and aggregation, structural dynamics and allostery, elasticity and mechanics, and protein folding and design. The sessions have been organized so that each topic is addressed using diverse approaches and techniques including simulation, spectroscopy, single molecule measurements, x-ray crystallography and a variety of biochemical and biophysical solution methods, with applications to basic and clinical science. The Biopolymers GRC is uniquely poised to foster multidisciplinary and interdisciplinary connections between chemistry, computer science, physics and biology. This meeting of scientists applying experimental and theoretical methods to study biological polymers encourages the exchange and discussion of results and ideas among participants with different backgrounds, thereby promoting interdisciplinary research activities. We encourage early registration and submission of abstracts for the poster session. We plan to select posters for short presentations for most of the meeting sessions. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=biopolym |
| Sujets apparentés | Chimie organique et polymères |
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| 46.Bioorganic Chemistry |
| Dates | 10 Jui 2012 → 15 Jui 2012 | [ID=454897] |
| Lieu | Andover, NH, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | The Gordon Research Conference on Bioorganic Chemistry was founded in 1992 to bring together scientists from a range of disciplines to present and discuss cutting-edge research at the interface between chemistry and biology. Both fundamental and applied research relevant to academia and industry are highlighted. To maintain a balance between these areas, the conference is organized by two co-chairs, one from academia and one from industry. The conference emphasizes the presentation of techniques or approaches that are broadly applicable across multiple areas of chemical and biological research. Traditionally, small molecules that probe, modulate, or mimic cellular components or processes as well as studies of biology at the molecular level have been of particular interest. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=bioorg |
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| 47.Metals in Medicine |
| Dates | 24 Jui 2012 → 29 Jui 2012 | [ID=455227] |
| Lieu | Andover, NH, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | The 2012 Gordon Conference on Metals in Medicine will present cutting-edge research on complexes of various metal ion complexes as drugs, as enzyme inhibitors and as imaging probes. The Conference will feature a wide range of topics including advances in platinum and other metal complexes as anti-cancer drugs, iron biochemistry, copper and zinc in physiology and disease, radionuclides in imaging and therapy, metalloproteins as medicinal targets, and metal ions in imaging from cells to animals to humans. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promote cross-disciplinary collaborations in the various research areas represented. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=metalsmed |
| Sujets apparentés | Physique appliquée: Biophysique; Pharmacologie et développement des médicaments |
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| 48.TETR2012 — 13th Tetrahedron Symposium |
| Dates | 26 Jui 2012 → 29 Jui 2012 | [ID=443492] |
| Lieu | Amsterdam, Pays-Bas |
| Résumé | We welcome participants to the 13th Tetrahedron Symposium, which will focus on the many crucial contributions that synthetic, medicinal chemistry and chemical biology are making to the life and medical sciences now and in the future. Chemistry is playing an increasingly pivotal role and chemists are often intimately involved at the forefront of the biological sciences whilst bringing to them the distinctive approaches of the rigorous chemical sciences. The Symposium will also highlight the key role of chemistry in the discovery and development of new therapeutic agents for human diseases. |
| Sujets | chemical biology, synthetic chemistry, bioorganic chemistry, medicinal chemistry |
| Page web | http://www.tetrahedron-symposium.elsevier.com/ |
| Sujets apparentés | Chimie organique et polymères; Pharmacologie et développement des médicaments |
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| 49.Seminar on Modeling of Biochemical Systems |
| Dates | 02 Jul 2012 → 05 Jul 2012 | [ID=424995] |
| Lieu | Girona, Espagne |
| Page web | http://iqc.udg.edu/xgironaseminar |
| Sujets apparentés | Simulation |
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| 50.Interfacing Chemical Biology and Drug Discovery |
| Dates | 04 Jul 2012 → 06 Jul 2012 | [ID=433424] |
| Lieu | Poitiers, France |
| Page web | http://www.medchem.fr |
| Sujets apparentés | Biologie moléculaire; Pharmacologie et développement des médicaments |
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| 51.Polymers in Medicine 2012 |
| Dates | 08 Jul 2012 → 12 Jul 2012 | [ID=334260] |
| Lieu | Praha, République tchèque |
| Organisateur | Institute of Macromolecular Chemistry AS CR |
| Page web | http://www.imc.cas.cz/sympo/77pmm/ |
| Contact | Dr Tomas Etrych, Institute of Macromolecular Chemistry AS CR, v.v.i. Heyrovského nám. 2 Praha CZ 162 06 Czech Republic; Tél.: (+420-296809331) |
| Sujets apparentés | Pharmacologie et développement des médicaments; Chimie organique et polymères |
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| 52.Biocatalysis |
| Dates | 08 Jul 2012 → 13 Jul 2012 | [ID=455329] |
| Lieu | Smithfield, RI, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | Biocatalysis encompasses the use of enzymes or whole cell systems for effecting the conversion of readily available, inexpensive starting materials to high value products. Enzymes are fully recyclable catalytic proteins that frequently display exquisite chemo-, enantio- and regioselectivity and operate under mild conditions of pH and temperature. These characteristics make them cost effective and sustainable catalysts for a wide range of chemical transformations. Modern tools of protein discovery, design and engineering aid the development of novel biocatalysts and their tailor-designed integration into industrial processes. Consequently, they find wide application in the production of pharmaceutical intermediates, novel materials and diagnostics,as well as fine, performance and agrochemicals. The Biocatalysis Gordon Conference highlights the best science, technologies and case studies responsible for the understanding, development and practical use of biocatalysts around the world. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=biocat |
| Sujets apparentés | Catalyse |
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| 53.COLN2012 — Colloids and Nanomedicine 2012 |
| Dates | 15 Jul 2012 → 17 Jul 2012 | [ID=443502] |
| Lieu | Amsterdam, Pays-Bas |
| Résumé | As with the previous meeting, a platform will be provided for first-rate reviews and discussions with leading international scientists and engineers working in the fields of biomaterials, drug delivery, sensors, imaging and diagnostics. This conference will provide a synthesis between medical/biological needs and advanced colloids/surface properties (the latter based on detailed physicochemical understanding).This in turn promising for a more rational materials and product development. |
| Sujets | Biomaterials Tissue engineering and regenerative medicine Drug delivery Biosensors Surfaces and colloids in imaging and diagnostics Microfluidics with colloidal systems Toxicology and risk assessment of nanomedicine systems Responsive colloids and materials Lipid and biomimetic membranes Proteins and peptides at interfaces Soft matter, surfactants, polymers in biological systems Adsorption, catalysis, and electrochemistry in biological systems Interfacial processes, capillarity and wetting in biological systems Novel phenomena and techniques |
| Page web | http://www.colloidsandnanomedicine.com |
| Sujets apparentés | Nanoparticules et émulsions |
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| 54.PREP2012 — 25th International Symposium, Exhibit and Workshops on Preparative and Process Chromatography |
| Dates | 15 Jul 2012 → 18 Jul 2012 | [ID=450368] |
| Lieu | Boston, États-Unis |
| Résumé | Outstanding program will be packed with papers on biochromatography, QbD, monoclonal antibodies, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, SMB, APIs, monoliths and new stationary phases, and more! 60+ oral presentations, 2-day Poster Session, 2½-day Exhibit, and workshops. The most recognized international meeting covering the latest developments in preparative and process liquid chromatography, separation science and technology, PREP2012. |
| Sujets | preparative chromatography, process chromatography, chromatographic separations, process liquid chromatography, fine chemicals, chiral molecules, active pharmaceutical ingredients, peptides, proteins, monoclonal antibodies, plasmids, vaccines, VLP?s, biopharmaceuticals |
| Page web | http://www.PREPsymposium.org |
| Contact | Janet Cunningham, ISSF 2012 Symposium/Exhibit Manager, Barr Enterprises; Email.: janetbarr@aol.com |
| Sujets apparentés | Formation en chromatographie (GC, HPLC, UPLC) |
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| 55.2012 AACC Annual Meeting |
| Dates | 15 Jul 2012 → 19 Jul 2012 | [ID=432375] |
| Lieu | Los Angeles, États-Unis |
| Organisateur | American Association for Clinical Chemistry |
| Page web | http://www.aacc.org/events/2012am/pages/default.aspx |
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| 56.Crystallisation - a Biological Perspective |
| Dates | 23 Jul 2012 → 25 Jul 2012 | [ID=425066] |
| Lieu | Leeds, Royaume-Uni |
| Page web | http://www.rsc.org/FD159 |
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| 57.Protein Cofactors, Radicals & Quinones |
| Dates | 29 Jul 2012 → 03 Aou 2012 | [ID=455640] |
| Lieu | South Hadley, MA, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | Many enzyme-catalyzed reactions are now known to require the assistance of complex cofactors that incorporate redox-active metal centers and organic molecules, including in many instances cofactors generated by post-translational modification of amino acid residues on the enzyme itself. The 2012 Protein Cofactors, Radicals, and Quinones Gordon Research Conference will bring together scientists who study the biogenesis and assembly of these complex cofactors, as well as the mechanisms of the catalytic chemistry carried out by these cofactors in the functioning enzymes. The conference will include reports of new research on aerobic and anaerobic radical enzymes, enzymes that utilize quinones and other cofactors derived via oxidation and crosslinking of amino acid residues, and the role of metal ions in both cofactor biogenesis and catalysis. This conference will bring together researchers from diverse disciplines including mechanistic enzymology, bioinorganic chemistry, bioorganic chemistry, spectroscopy, computational chemistry, and structural biology. An important part of this Gordon Conference is the poster sessions, which provide opportunities to present and informally discuss your most recent results. All conferees are encouraged to participate by presenting a poster; several speakers will be invited to present short talks based on the submitted poster abstracts. This Gordon Conference has a strong history of promoting participation by young scientists, including graduate students, postdoctoral associates, and assistant professors, and again for the 2012 conference we would especially like to encourage applications and poster abstract submissions by young scientists. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=protcofac |
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| 58.Medicinal Chemistry |
| Dates | 05 Aou 2012 → 10 Aou 2012 | [ID=455829] |
| Lieu | New London, NH, États-Unis |
| Organisateur | Gordon Research Conferences |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=medchem |
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| 59.Biomineralization |
| Dates | 12 Aou 2012 → 17 Aou 2012 | [ID=455874] |
| Lieu | New London, NH, États-Unis |
| Organisateur | Gordon Research Conferences |
| Résumé | The Gordon Research Conference on Biomineralization is exploring the basic principles by which organisms synthesize, control and make use of minerals, as well as potential applications of these. Spectacular advances have been made in the last years and are impacting various scientific fields, from biology to geology, from medicine to materials science and from evolutionary sciences to engineering. The central goal of this GRC is to create a stimulating environment for scientists from all these disciplines to discuss latest ideas and recent advances on how minerals interact with biomolecules, on how cellularly driven biomineralization is regulated by extracellular matrix molecules, on how the structures of mineralized tissues relate to their function and on how these principles might influence our thinking in materials science and engineering. The conference will cover all kinds of biominerals, including carbonates, phosphates, oxides and silica, in vertebrates, invertebrates and plants. It will also address human health issues related to abnormal mineralization or diseases connected to mineral growth and homeostasis in the skeleton or in teeth. The great success which this GRC experienced in the last years is largely due to its lively afternoon poster sessions, complementing the invited lectures. This provides the best opportunity to present latest research and exchange ideas in a more informal setting and all conferees are encouraged to submit and present posters. As done in previous conferences, 8-10 poster contributions will be selected for short oral presentations. All this has made this GRC very attractive for young scientists and - as the consequence of a vote in 2010 - the GRC on bimineralization 2012 will be complemented for the first time by a Gordon Research Seminar preceding the meeting. |
| Page web | http://www.grc.org/programs.aspx?year=2012&program=biomin |
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| 60.IFBLS2012 — The 30th World Congress of Biomedical Laboratory Science |
| Dates | 18 Aou 2012 → 22 Aou 2012 | [ID=398186] |
| Lieu | Berlin, Allemagne |
| Résumé | Biomedical laboratory science plays an important role in the public and private health care system throughout the world, providing excellent clinical laboratory service for the wellbeing of patients. It is a great challenge to all biomedical scientists to further develop despite permanent changes (move along with constant changes) in medicine and public health areas and the constant threat of explosive increases in costs. It is our primary common goal to develop the profession of biomedical scientists and to emphasize our role in the health care system. The 30th World Congress is a global event and hosts a large number of biomedical scientists, researchers, laboratory workers and business executives from around the world to discuss and share the latest knowledge in biomedical laboratory science. Furthermore the congress will strengthen co-operation between relevant organizations and built networks between colleagues, scientists and friends during this scientific gathering. |
| Page web | http://www.ifbls-dvta2012.com/ |
| Sujets apparentés | Médecine (en général) |
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| 61.73rd Harden - Machines on genes II - The central dogma at the interface of biology, chemistry and physics |
| Dates | 19 Aou 2012 → 23 Aou 2012 | [ID=423176] |
| Lieu | Oxford, Royaume-Uni |
| Résumé | The replication, maintenance and transcription of the genome require an array of protein machines including polymerases, helicases, translocases, nucleases, recombinases and topoisomerases, often functioning as components of multi-protein complexes. Machines on Genes II will bring together scientists with an interest in multi- and inter-disciplinary approaches for unravelling the anatomy, architecture and mechanisms of these remarkable molecular machines. The conference will cover topics in DNA replication, recombination, repair and transcription and will showcase the latest work of world leaders in the fields of structural biology, chemical biology and novel biophysical methods including single-molecule detection. |
| Page web | http://www.biochemistry.org/Conferences/AllConferences/tabid/379/View/Conference/Filter/40FC/Page/1/MeetingNo/73hdn/MeetingID/2401/Default.aspx |
| Sujets apparentés | Biologie moléculaire |
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| 62. 9th International Symposium on Biomolecular Chemistry |
| Dates | 25 Aou 2012 → 29 Aou 2012 | [ID=461164] |
| Lieu | Pékin, Chine |
| Page web | http://isboc9.dconference.cn/dct/page/1 |
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| 63.EFMC-ISMC 2012 — 22nd International Symposium on Medicinal Chemistry |
| Dates | 02 Sep 2012 → 06 Sep 2012 | [ID=424993] |
| Lieu | Berlin, Allemagne |
| Page web | http://www.ismc2012.org |
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| 64.37th FEBS Congress — 37º Congreso Europeo de la Federación de Sociedades Europeas de Bioquímica |
| Dates | 04 Sep 2012 → 09 Sep 2012 | [ID=444977] |
| Lieu | Séville, Espagne |
| Page web | http://www.febs.com |
| Sujets apparentés | Biologie moléculaire |
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| 65.22nd IUBMB Congress — 22º Congreso Internacional de la Unión Internacional de Bioquímica y Biología Molecular |
| Dates | 04 Sep 2012 → 09 Sep 2012 | [ID=444998] |
| Lieu | Séville, Espagne |
| Page web | http://www.fibes.es |
| Sujets apparentés | Biologie moléculaire |
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| 66.SFRRI — 16th Biennial meeting for the Society for Free Radical Research International |
| Dates | 06 Sep 2012 → 09 Sep 2012 | [ID=432389] |
| Lieu | Londres, Royaume-Uni |
| Page web | http://sfrrimeeting.org/index.html |
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| 67.Lipids and Membrane Biophysics |
| Dates | 11 Sep 2012 → 13 Sep 2012 | [ID=424972] |
| Lieu | Londres, Royaume-Uni |
| Page web | http://www.rsc.org/FD161 |
| Sujets apparentés | Biologie moléculaire |
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| 68.G-protein-coupled-receptors: from structural insights to functional mechanisms - co-organized by the Biochemical Society and Monash University |
| Dates | 12 Sep 2012 → 14 Sep 2012 | [ID=423137] |
| Lieu | Prato, Italie |
| Résumé | A two-day meeting based at Prato in Italy, which will consider recent advances in G-protein coupled receptor structure and function, building on new concepts arising from biophysics, crystallography, pharmacology and cell biology |
| Sujets | Crystal structures of family A GPCRs, Ligand binding and activation of family A GPCRs, Ligand binding and activation of family B GPCRs, Novel ligands for GPCRs and drug design, RAMPs and other accessory proteins, GPCR oligomerisation, Trafficking of GPCRs, GPCR signalling to ion channels, Single molecule studies of GPCRs |
| Page web | http://www.biochemistry.org/Conferences/AllConferences/tabid/379/View/Conference/Filter/40FC/Page/1/MeetingNo/sa124/MeetingID/2401/Default.aspx |
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| 69.International Conference on Bioinspired and Biobased Chemistry & Materials |
| Dates | 03 Oct 2012 → 05 Oct 2012 | [ID=456286] |
| Lieu | Nice, France |
| Page web | http://www.nice-conference.com/ |
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| 70.Aboveground-belowground interactions: technologies and new approaches |
| Dates | 08 Oct 2012 → 10 Oct 2012 | [ID=448170] |
| Lieu | Charles Darwin House, London, Royaume-Uni |
| Organisateur | Biochemical Society |
| Page web | http://www.biochemistry.org/Conferences/AllConferences/tabid/379/View/Conference/MeetingNo/BSB002/Default.aspx |
| Sujets apparentés | Chimie de l'environnement, géochimie |
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| 71. 7th International IUPAC Symposium on Mycotoxins & Phycotoxins |
| Dates | 05 Nov 2012 → 09 Nov 2012 | [ID=461245] |
| Lieu | Rotterdam, Pays-Bas |
| Page web | http://www.wmfmeetsiupac.org |
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| 72.WMF meets IUPAC, 7th World Mycotoxin Forum and XIII IUPAC International Symposium on Mycotoxins and Phycotoxins |
| Dates | 05 Nov 2012 → 09 Nov 2012 | [ID=463613] |
| Lieu | The Hague, Pays-Bas |
| Page web | http://www.bastiaanse-communication.com/ |
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| 73.TETW2012 — 13th Tetrahedron Symposium (Asia) - Challenges in Bioorganic & Medicinal Chemistry |
| Dates | 27 Nov 2012 → 30 Nov 2012 | [ID=450134] |
| Lieu | Taipei, Taïwan |
| Résumé | Chemistry is playing an increasingly pivotal role and chemists are often intimately involved at the forefront of the biological sciences whilst bringing to them the distinctive approaches of the rigorous chemical sciences. The Symposium will also highlight the key role of chemistry in the discovery and development of new therapeutic agents for human diseases. |
| Sujets | chemical biology, synthetic, bioorganic chemistry, medicinal chemistry, sequencing nucleic acids: from chemistry to life sciences and medicine, Oligonucleotide-based tools for pharmacology and nano-engineering, The future of kinase drug discovery - challenges and opportunities, Vaccines as a new paradigm for the treatment of drug addiction, Fragment-based drug discovery: a decade of thinking small, Chemical biology of nanomedicines, Modulation of DNA damage-response pathways in cancer therapy, The chemical biology of protein splicing, Molecular design for selective recognition and reaction with RNA Target identification for biologically relevant small molecules, Total Synthesis as a Vehicle for Interrogating Biosynthetic and Biomechanistic Puzzles |
| Page web | http://www.tetrahedronsymposiumasia.com/ |
| Contact | Steve Jebbett, Conference Secretariat; Tél.: (+86 18 2109 58795); Email.: customerservice-tetrahedron12@elsevier.com |
| Sujets apparentés | Chimie combinatoire; Pharmacologie et développement des médicaments |
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| 74.Congress of Toxicology |
| Dates | 30 Jui 2013 → 04 Jul 2013 | [ID=433439] |
| Lieu | Seoul, Corée du Sud |
| Page web | http://www.ict2013seoul.org/ |
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