Services aux conférences Mandl

Résumé: This course in medicinal chemistry sets out to train organic chemists to understand the key factors in discovering a new drug substance, from target selection, through lead generation and lead optimisation, to the selection of a development candidate. The course will cover aspects of the drug discovery process such as structure activity relationships, the use of computational chemistry in drug discovery, ADME and safety issues and highlights some of the reasons for project failure.

Résumé: This 3-day training course for industrial chemists covers the advanced principles of aromatic heterocyclic chemistry. Concentrating on a wide range of molecules with 1-4 heteroatoms (mainly nitrogen), their importance in industry, synthesis and strategy are discussed, interspersed with tutorials and problem sessions. This course has been designed to follow the basic course.

Résumé: This course is for Medicinal Chemists and Project Managers who wish to gain an improved feel for drug discovery biology. The biological world is immense and therefore the course drills down to provide an overview of only those key areas of biology relevant to the Medicinal Chemist in a drug discovery environment. The order in which various biological attributes are generated in the total drug discovery process is also provided in the course. At the end of the course the Medicinal Chemist should be better positioned to analyse and interpret the biological data used to evaluate their compounds.