Meetings/Workshops on Molecular Biology in Canada

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1
Keystone Symposia: Obesity and Adipose Tissue Biology
10 Feb 2019 - 14 Feb 2019 • Banff, Alberta, Canada
Abstract:
Obesity is a growing worldwide epidemic, increasing co-morbid conditions, such as diabetes. The joint conferences on “Obesity and Adipose Tissue Biology” and “Functional Neurocircuitry of Feeding and Feeding Disorders” are aimed to foster cross-talk between these research areas. Adipose tissue is an endocrine organ that is both controlled by and sends signals to the brain and other organs. In addition, obesity causes an inflammatory state in the adipose tissue. The recognition that brown/beige adipose tissue is active in adult humans has triggered interest in understanding the physiology and relative importance of these tissues. Exercise and bariatric surgery are known to elicit profound metabolic benefits in type 2 diabetes, although the underlying mechanisms remain unclear. This conference will bring together cell biologists, biochemists, geneticists, physiologists, drug developers and clinical researchers, thereby facilitating knowledge exchange and interactions leading to elucidation of better treatments for obesity and diabetes. Specifically, it will examine recent advances in our understanding of brown/beige adipose tissue function; obesity-induced adipose inflammation; control of adipose tissue, appetite and energy metabolism; endocrine and paracrine signaling via secreted factors; molecular mechanisms of metabolic signaling; emerging topics, including long noncoding RNA and the gut microbiome; and approaches to drug development and the treatment of obesity and diabetes.
Contact:
Attendee Services;     Phone: [970.262.1230];     Email: info@keystonesymposia.org
Topics:
metabolic diseases, diabetes, obesity, adipose tissue, gut microbiome
Event listing ID:
1136851
2
Keystone Symposia: Genome Engineering - From Mechanisms to Therapies
19 Feb 2019 - 23 Feb 2019 • Victoria, BC, Canada
Abstract:
The use of programmable nucleases such as CRISPR-Cas systems, ZFNs and TALENs has revolutionized cell biology by providing the ability to manipulate specific genetic and epigenetic states within living cells. These systems have been broadly applied as tools in research settings and increasingly are being used to develop improved models of disease and engineer cells for therapeutic purposes. Together with other DNA-modifying systems such as recombinases, integrases and transposases, it is now possible to introduce mutations that will model human disease, build complex synthetic signaling networks to perform regulated functions, and design cells to target specific disease states. Improvements to the methods involved requires understanding enzyme structures and mechanisms and how they intersect with cellular DNA repair systems. The intersection of this basic science with engineering approaches and improved cellular models is revolutionizing our understanding and treatment of human disease. The goal of this Keystone Symposia conference is to bring together those developing and studying genome engineering tools with groups who are applying them to build new disease models, identify disease mechanisms and drug targets, and develop cell-based therapeutics and genetic medicines.
Contact:
Attendee Services;     Phone: [970.262.1230];     Email: info@keystonesymposia.org
Topics:
genetics, genomics, CRISPR-Cas systems, DNA, gene editing, genome engineering, basic research, technologies, molecular biology
Event listing ID:
1156396
Related subject(s):
3
Keystone Symposia: Diabetes - Innovations, Outcomes and Personalized Therapies
03 Mar 2019 - 07 Mar 2019 • Whistler, British Columbia, Canada
Abstract:
Scholarship and Discounted Abstract Deadline: November 19, 2018

Diabetes remains a public health challenge of epidemic proportions. Modern treatment algorithms are evolving to recommend higher focus on personalized approaches to diabetes care. However, as diabetes remains a disease characterized by excess elevation of a plasma biomarker, glucose, further refinement of our understanding of the disease and its comorbidities is required to provide optimal guidance for precision medicine. Advancement of research technologies and the ability to handle large data sets have enabled systems biology approaches to unravel different etiologies and pathophysiological consequences of diabetes. Future diabetes discovery efforts will focus on pairing knowledge about genetic risk and environmental triggers of diabetes-associated pathologies. Using deep phenome characterization and molecular network analyses diabetes, researchers will be able to launch modern translational approaches to diabetes care innovation. The objectives of the conference are to provide directional guidance for future pressure points of diabetes care, and focus on specific diabetes complications representing particular unmet needs. Further, forefront discoveries of genetic risk determinants and their molecular mechanisms will be presented together with lively debates about the translatability of such insights into novel curative therapies. This symposium is paired with "Unraveling the Secrets of Kidney Disease."

Contact:
Attendee Services;     Phone: [970.262.1230];     Email: info@keystonesymposia.org
Topics:
Diabetes, metabolic diseases, obesity
Event listing ID:
1139293
4
Keystone Symposia: Epigenetics and Human Disease
17 Mar 2019 - 21 Mar 2019 • Banff, Alberta, Canada
Abstract:
Epigenetics is a major mechanism in human health and disease. Data from a range of diseases (cancer, neurological and immunological disorders) have uncovered altered epigenomes arising from mutations, altered expression and/or copy number alterations of numerous epigenetic factors (histones, DNA and chromatin modifying enzymes, reader proteins, chromatin modulators and noncoding RNAs). Genome-wide analyses have illustrated the relationship between altered epigenetic states (e.g., modified DNA, histones and chromatin packaging) and disease onset and progression. Furthermore, both local and long-range nuclear chromatin architecture are increasingly recognized as major contributors to normal and pathologic epigenetic states. This conference, held jointly with the “3D Genome” conference, will cover the most current knowledge of epigenetic events modulating nuclear function (gene expression regulation, enhancer modulation, domains and structural organization as well as cell division and differentiation), while relating this to normal and disease models.
Contact:
Attendee Services;     Phone: [970.262.1230];     Email: info@keystonesymposia.org
Topics:
DNA, noncoding RNAs, chromatin, genetics, genomics, molecular biology, cancer
Event listing ID:
1156312
Related subject(s):
5
Keystone Symposia: 3D Genome - Gene Regulation and Disease
17 Mar 2019 - 21 Mar 2019 • Banff, Alberta, Canada
Abstract:
Transcription of the eukaryotic genome is not only driven by the cis regulatory elements embedded in the linear DNA sequence but also by the way chromosomes fold in the three-dimensional (3D) nuclear space. Growing evidence has pointed to a key role of the 3D genome architecture in gene regulation and human disease; however, the details of dynamic chromatin organization in different cell types remain opaque. Additionally, how chromatin organization shapes the gene regulatory program and influence disease pathogenesis has not been fully elucidated. The major objective of this conference is to accelerate the study of 3D genome organization; particularly with regard to gene regulation and human disease.
Contact:
Attendee Services;     Phone: [970.262.1230];     Email: info@keystonesymposia.org
Topics:
molecular biology, genetics, genomics, 3D genome architecture, epigenomics, computational biology
Event listing ID:
1156333
6
19w5226 — The Topology of Nucleic Acids: Research at the Interface of Low-Dimensional Topology, Polymer Physics and Molecular Biology
24 Mar 2019 - 29 Mar 2019 • Banff, Alberta, Canada
7
19w5080 — Bridging Cellular and Tissue Dynamics from Normal Development to Cancer: Mathematical, Computational, and Experimental Approaches
16 Jun 2019 - 21 Jun 2019 • Banff, Alberta, Canada

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Conference-Service.com offers, as part of its business activities, a directory of upcoming scientific and technical meetings. The calendar is published for the convenience of conference participants and we strive to support conference organisers who need to publish their upcoming events. Although great care is being taken to ensure the correctness of all entries, we cannot accept any liability that may arise from the presence, absence or incorrectness of any particular information on this website. Always check with the meeting organiser before making arrangements to participate in an event!

Last updated: 06 December 2018