Meetings/Workshops on Geriatrics in the United States (USA)

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1
FASEB SRC — Reversible Acetylation on Health and Disease (HDACs)
06 Aug 2017 - 11 Aug 2017 • Big Sky, Montana, United States
Abstract:
Over the past few years, the “epigenetic” regulation of the genome has become increasingly important to understanding both the etiology and fundamental mechanisms of aging and age-related diseases. Key to epigenetic regulation are two classes of lysine-modifying enzymes, the histone deacetylases (sirtuins and HDACs) and the histone acetyltransferases (HATs). Both classes of enzyme are critical for maintaining youthful gene expression patterns, cell cycle progression, DNA repair, stem cells, mitochondria, cell fate, differentiation, cognition, energy utilization, and the pathogenesis of most age-related diseases. Alterations in sirtuin and HDAC function have been linked to neurodegenerative disorders, muscle wasting, cardiac hypertrophy, cancer, HIV infection, and more generally the process of aging. Several HDAC inhibitors have been approved by FDA to treat various cancers. Small molecule modulators of sirtuins are currently in clinical trials for the treatment of cancers, neuromuscular disorders, inflammatory and metabolic disorders. With particular relevance to aging, the sirtuins, a subclass of HDAC, were first identified in yeast genetic studies as regulators of lifespan and the health benefits of dietary restriction. Activation or overexpression of sirtuins have been shown to protect mice and primates from diseases of aging, and extend mean and maximum lifespan of mice. Therefore, a thorough understanding of sirtuins and HDACs is required, not merely for understanding the regulation of chromatin structure, gene regulation and protein function, but also because these enzymes are intimately involved in normal and abnormal cellular processes that greatly impact human health. Although targeting HATs for therapeutic purposes has been relatively slow compared to targeting deacetylases, exciting new progress has also been made in recent years. Importantly, targeting the bromodomains present in many HATs has attracted a lot of attention lately.
Contact:
FASEB SRC Staff;     Phone: [3016347010];     Email: src@faseb.org
Topics:
aging, stem cell, cancer, differentiation, structural biology
Event listing ID:
871094
Related subject(s):
2
2018 MCI Symposium — 16th Annual Mild Cognitive Impairment Symposium, Special Topic Workshop and Alzheimer's Public Educational Forum
20 Jan 2018 - 21 Jan 2018 • Miami Beach, United States
Abstract:
This CME/CE accredited event will attract over 250 attendees from around the world, including academic and industry scientists, government and association/foundation representatives, professional healthcare providers and, for the Public Forum, family caregivers.
Contact:
2018 MCI Conference Secretariat;     Phone: [1.224.938.9523];     Email: meetings@worldeventsforum.com
Topics:
Alzheimer's, APOE, Epigenetics, LOAD, Neuropsychology, MCI, Bilingualism, Imaging, Neuroplasticity, AD
Event listing ID:
916924
Related subject(s):
3
American Geriatrics Society Annual Scientific Meeting 2018
03 May 2018 - 05 May 2018 • Orlando, United States
Abstract:
The AGS Annual Scientific Meeting is the premier educational event in geriatrics, providing the latest information on clinical care, research on aging, and innovative models of care delivery.  The 2018 Annual Meeting will address the educational needs of geriatrics professionals from all disciplines.  Physicians, nurses, pharmacists, physician assistants, social workers, long-term care and managed care providers, health care administrators, and others can update their knowledge and skills through state-of-the-art educational sessions and research presentations.   The 2018 Annual Meeting offers many continuing education sessions, including invited symposia, workshops, and meet-the-expert sessions.  Sessions will include information about emerging clinical issues, current research in geriatrics, education, health policy, and delivery of geriatric health care.
Event listing ID:
652112

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