Meetings/Workshops on Stemm-cell research & therapy in the United States (USA)

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1
FASEB SRC — Hematologic Malignancies
23 Jul 2017 - 28 Jul 2017 • Saxtons River, VT, United States
Abstract:
This SRC focuses on bringing together biochemists, geneticists, molecular biologists and clinicians interested in the pathophysiology of the leukemias and lymphomas, and the development of novel therapies for these diseases. Leukemia and lymphoma has provided a number of key paradigms for molecularly targeted cancer therapy, as illustrated by the remarkable success of all-trans-retinoic acid for the treatment of acute promyelocytic leukemia and tyrosine kinase inhibitor therapy for chronic myelogenous leukemia. New and promising small-molecule compounds and antibodies targeting epigenetic regulators, surface receptors and downstream signaling pathways are currently under development and will be discussed at this meeting. Added to these examples of targeted therapy, immunotherapy, including checkpoint inhibition and modified T cell-based therapies have emerged as important future anti-leukemia/lymphoma treatments.
Contact:
FASEB SRC Staff;     Phone: [3016347010];     Email: src@faseb.org
Topics:
cancer, stem cell, hematology, genetics, molecular biology, lymphoma/leukemia
Event listing ID:
876965
Related subject(s):
2
FASEB SRC — Molecular Mechanisms of Immune Cell Development and Function
30 Jul 2017 - 04 Aug 2017 • Snowmass Village, Colorado, United States
Abstract:
This SRC will include a keynote talk by Dan Litmann, a leader in the field, and formal sessions on (1) Early lymphocyte progenitors, (2) Mechanisms that underpin lymphocyte development, (3) Transcriptional regulation of lymphocyte differentiation, (4) Antigen receptor assembly, (5) Molecular and physical mechanisms that promote lymphocyte cell fate, (6) B cell activation and neoplasia, (7) The regulation of the immune responses, 8) Innate immunity and (9) Molecular pathways in innate immunity. These sessions are each anchored by 4 invited speakers with 3 shorter talks chosen from abstracts. The meeting will also include two poster sessions and two workshops consisting of short presentations chosen from submitted abstracts. By highlighting common and contrasting uses of similar mechanisms, the meeting will reveal unexpected synergies between areas of molecular immunology that are traditionally considered distinct. Such discoveries are enhanced by the program’s emphasis on mixing national and international experts with young scientists, including postdoctoral fellows and graduate students, among the presenters in an open atmosphere of scientific exchange. Finally, a large number of oral presentations will be selected from the abstracts.
Contact:
FASEB SRC Staff;     Phone: [3016347010];     Email: src@faseb.org
Topics:
immunology, genomics, Molecular Biology, Stem cell
Event listing ID:
876941
Related subject(s):
3
FASEB SRC — Reversible Acetylation on Health and Disease (HDACs)
06 Aug 2017 - 11 Aug 2017 • Big Sky, Montana, United States
Abstract:
Over the past few years, the “epigenetic” regulation of the genome has become increasingly important to understanding both the etiology and fundamental mechanisms of aging and age-related diseases. Key to epigenetic regulation are two classes of lysine-modifying enzymes, the histone deacetylases (sirtuins and HDACs) and the histone acetyltransferases (HATs). Both classes of enzyme are critical for maintaining youthful gene expression patterns, cell cycle progression, DNA repair, stem cells, mitochondria, cell fate, differentiation, cognition, energy utilization, and the pathogenesis of most age-related diseases. Alterations in sirtuin and HDAC function have been linked to neurodegenerative disorders, muscle wasting, cardiac hypertrophy, cancer, HIV infection, and more generally the process of aging. Several HDAC inhibitors have been approved by FDA to treat various cancers. Small molecule modulators of sirtuins are currently in clinical trials for the treatment of cancers, neuromuscular disorders, inflammatory and metabolic disorders. With particular relevance to aging, the sirtuins, a subclass of HDAC, were first identified in yeast genetic studies as regulators of lifespan and the health benefits of dietary restriction. Activation or overexpression of sirtuins have been shown to protect mice and primates from diseases of aging, and extend mean and maximum lifespan of mice. Therefore, a thorough understanding of sirtuins and HDACs is required, not merely for understanding the regulation of chromatin structure, gene regulation and protein function, but also because these enzymes are intimately involved in normal and abnormal cellular processes that greatly impact human health. Although targeting HATs for therapeutic purposes has been relatively slow compared to targeting deacetylases, exciting new progress has also been made in recent years. Importantly, targeting the bromodomains present in many HATs has attracted a lot of attention lately.
Contact:
FASEB SRC Staff;     Phone: [3016347010];     Email: src@faseb.org
Topics:
aging, stem cell, cancer, differentiation, structural biology
Event listing ID:
871072
Related subject(s):
4
Oncology Summit 2017 — International Oncology Summit
27 Nov 2017 - 28 Nov 2017 • Atlanta, United States
Abstract:
Allied Academies invites all the participants from all over the world to attend 'International Oncology Summit’ during November 27-28, 2017 in Atlanta, Georgia, USA which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions. This Summit has the platform to fulfill the prevailing gaps in the transformation of this science of hope, to serve promptly with solutions to all in the need. International Oncology Summit will have an anticipated participation of 120+ delegates across the world to discuss the conference goal
Contact:
Rayan Wayne;     Phone: [8008582189];     Email: oncologyevents@alliedconferences.org
Topics:
Cancer Conferences USA, Cancer Meetings 2017, Oncology Conferences USA, Oncology Symposiums 2017, Oncology Conferences Atlanta.
Event listing ID:
902433
Related subject(s):

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