Konferenzen zum Thema Physiologie und Metabolismus des Menschen in Italien

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1
Single Cell Omics
17. Sep 2017 - 24. Sep 2017 • Siena, Italien
Zusammenfassung:
Neuroscience has entered a critical phase, with several international large-scale efforts devoted to the analysis and understanding of brain function. Studies exploiting new technologies for defining the connections in the brain, driving neuronal activity and modeling of neuronal processing are each hampered by our incomplete knowledge of the brain’s constituent parts. Fortunately, a bevy of single cell analyses are now being deployed to better understand the cells that constitute the functioning nervous system. These approaches offer insights into how cells function individually as the building blocks for understanding how they work in ensemble to create functional pathways. A set of emerging tools are available to assess the molecular and cell biology of single cells, including genomic analyses of somatic mutations, epigenomics to explain the influence of the environment upon genome expression, and transcriptomics to gain insight into the capacity of a cell to synthesize proteins and modulate its environment. Powerful technologies permit a variety of cell constituents to be addressed, including proteins, post-translational modifications, peptides and metabolites. Novel biosensors offer parallel analyses of cellular physiological states, reporting on the pH, membrane voltage and metabolic state. Multiplexed together, such methodologies offer a far more complete biological understanding than the more typical gene expression analyses, providing a rich picture of each single cell’s biology in their normal context – information needed to fully interpret the meaning of results from transcriptomics and proteomics studies.This Advanced Course is designed to provide the foundational knowledge needed to critically evaluate the design and execution of single cell omic studies, through daily lectures by the Faculty, critical reading of papers and extensive didactic discussion sessions. In the sessions, discussion will focus on the proper framing of scientific questions to best utilize these techniques, the limitations and advantages of each technique, and what the data can tell us about neuronal function.
Kontakt:
Francesca Martini;     Tel.: [+39.0577.146.0003];     Email: info@nsas.it
Eintrags-ID:
868391
Verwandte Fachgebiete:
2
The Neuroscience of Obesity
17. Sep 2017 - 24. Sep 2017 • Siena, Italien
Zusammenfassung:
Significant progress has been made in recent years in the understanding the role of the nervous system in obesity. Not only several different neuronal pathways, neurotransmitters and hormones have been identified as major players in the regulation of feeding and body weight, bu also energy balance in mammals is controlled by a complex network of interacting feedback mechanisms that involve peripheral organs in addition to higher brain centers. This Advanced Course will provide conceptual- and cutting edge technological framework for state-of-the-art of neuroscience on energy metabolism. The Faculty represents diverse expertise in molecular, cellular, circuit and behavioral approaches on contemporary questions regarding the role of the brain in systemic metabolism regulation and how the periphery affects complex brain functions via neuronal circuits and brain cells.
Kontakt:
Francesca Martini;     Tel.: [+39.0577.146.0003];     Email: info@nsas.it
Eintrags-ID:
868412
Verwandte Fachgebiete:

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Stand vom 07. Januar 2017