The thirteenth biennial International Conference on Fatigue Damage of Structural Materials will be held in scenic Cape Cod at the DoubleTree by Hilton Hotel, Hyannis, USA from 13-18 September 2020. This prestigious and long running conference will bring together delegates from around the world to discuss how to characterize, predict, and analyze the fatigue damage of structural materials. The conference will maintain its unique and traditional format of single-session 30 min oral presentations that facilitates sufficient time for a thorough technical presentation, follow-up discussions, and collegial debate of the cutting-edge issues in the field of fatigue. The entire conference program is deliberately scheduled with equal significance to our poster sessions, themed in relation to the oral presentations, and assessed for awards via a peer review process. Furthermore, all delegates are strongly encouraged to submit a paper to be published in a conference specific Special Issue of International Journal of Fatigue. We welcome our colleagues to join us once again in the charming and historic city of Hyannis, MA on Cape Cod; our returning delegates will be delighted to find that we are returning to the more modern and updated conference venue used in 2018. We are excited to invite members of the domestic and international fatigue community to join us (again or for the first time) as we continue to advance the knowledge and understanding of the mechanics, materials, environmental, and computational aspects of fatigue damage in structural materials.