Relevant topics include (but are not limited to) the following: • AI and Cognition, Cognitive Mechatronics, Human-Machine Interaction, Cobotics, Model-based design and configuration tools for healthcare and well-being, AI methods for medical device testing • Systems for management of health and care (mental health, pain, neurological disorders, sight, hearing, balance, space awareness; sensory based physiological and psychological non-invasive measurements, preventive healthcare, m-healthcare, e-healthcare, integrated care, serious games, electronic health record, self-management, patient-centered systems for survivorship, palliation and/or end-of-life care) • Precision medicine • ICT for in-silico trials • Implantable medical devices • Computational methods for medical device • Models for human-device interaction for medicine • Systems promoting access to the socio-economical and cultural environment • Age-friendly systems for active and healthy aging (telepresence, robotics solutions, innovative solutions for independent living, innovative elderly care, integrated care, age-related risks prevention/detection) • Multimodal assistive ICT devices to empower people with sensory, cognitive, motor, balance and spatial impairments • ICT systems to improve the quality of life and for daily life activities assistance (education, recreation, and nutrition) • Smart living homes and wearables (Intelligent and personalized digital solutions for sustaining and extending healthy and independent living; personalized early risk detection and intervention) • New experimental validation methods with end-users • Standardization, certification, labeling, privacy, security and communication issues (related to aging well, to sensory impairment) High-quality original submissions that address such future issues, show the design and evaluation in (near-) real scenarios, explain how to benchmark systems, and outline the education and training procedures for acquiring new perceptual skills while using such systems are welcome. Research and technical papers are expected to present significant and original contributions validated with the targeted end-users. Early works and works- in-progress are invited to submit a short or demo paper. Submissions should clearly state the progress beyond the existing state-of- the-art and the expected societal benefits of the developed technology. When possible, validate scenarios with the target user groups and well-identified technology readiness levels (https://en.wikipedia.org/wiki/Technology_readiness_level) should be at least outlined.