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Conférences - Biochimie et chimie médicale - États-Unis

Conference-Service.com met à la disposition de ses visiteurs des listes de conférences et réunions dans le domaine scientifique. Ces listes sont publiées pour le bénéfice des personnes qui cherchent une conférence, mais aussi, bien sûr, pour celui des organisateurs. Noter que, malgré tout le soin que nous apportons à la vérification des données entrées dans nos listes, nous ne pouvons accepter de responsabilité en ce qui concerne leur exactitude ou étendue. Pensez donc à vérifier les informations présentées avec les organisateurs de la conférence ou de la réunion avant de vous engager à y participer!

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1.Keystone Symposia: Sirtuins in Metabolism, Aging and Disease
 Dates 12 Fév 2012 → 17 Fév 2012
[ID=427702] Haut de la page
 LieuTahoe City, CA, États-Unis
 Résumé Sirtuins comprise a unique class of NAD+-dependent enzymes that modify multiple protein substrates to execute diverse biological functions. Sirtuins are key regulators of clinically important cellular and organismal processes including metabolism, cell division and aging. The desire to understand the important determinants of human health and lifespan has resulted in a firestorm of work on the seven mammalian sirtuins in the past decade. The implication of sirtuins in medically important areas such as diabetes, cancer, cardiovascular dysfunction and neurodegenerative disease has catapulted them to a prominent status as potential targets for nutritional and therapeutic development. The Keystone Symposia meeting on Sirtuins in Metabolism, Aging and Disease will address fundamental questions on the regulation, biochemical, molecular and cellular mechanisms and pathways of sirtuins. The significance of sirtuin-dependent regulation of homeostasis with respect to diverse biological organisms will be discussed. We envision that this meeting will evaluate the relevance of sirtuin biology in various human conditions, and provide a unique environment for discussing specific therapeutic strategies.
 Sujets Cell Biology, Small Molecule Chemistry, Drug Discovery, Metabolic Diseases, Neurodegenerative Disease, Neurobiology, Cancer Prevention, Aging, Cell Biology, Keystone Symposia, Sirtuins, Metabolism
 Page web http://www.keystonesymposia.org/12B2
 Sujets apparentés Biologie; Médecine (en général)
2.Mastering Medicinal Chemistry Summit
 Dates 21 Fév 2012 → 23 Fév 2012
[ID=445561] Haut de la page
 LieuSan Francisco, États-Unis
 Page web http://www.triconference.com/mch/
3.Keystone Symposia: ApoE, Alzheimer's and Lipoprotein Biology
 Dates 26 Fév 2012 → 02 Mar 2012
[ID=427762] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé Apolipoprotein E4 (ApoE4) genotype is the primary risk factor for late-onset Alzheimer?s Disease. Approximately one fifth of the human population are ApoE4 carriers, yet more than 17 years after its discovery, the molecular basis by which this common allele causes neurodegeneration is still not understood. One major reason is the lack of effective communication between lipid researchers who have investigated the role of ApoE as a plasma lipid transport protein, and neuroscientists who are unfamiliar with the complex biochemistry of lipid metabolism and the cell biology of ApoE receptors. This is confounded by the methodological difficulty of studying lipid metabolism and lipoprotein transport in the brain and the paucity of pioneering work tackling this problem. Yet, the solution to one of the most pressing socioeconomic problem of our times, the looming Alzheimer?s Disease epidemic, depends on our ability to dissect and understand the molecular mechanism by which ApoE4 is causing this disease. The purpose of this highly interdisciplinary meeting on ApoE, Alzheimer?s and lipoprotein biology is to bring together a critical mass of experts with complementary expertise from these different fields, but who do not normally collaborate or attend the same conferences. In this manner, we envisage this meeting serving as the main catalyst for communication and collaboration between lipid and lipoprotein researchers, neurogeneticists, cell biologists and synaptic neurophysiologists. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Clinical and Molecular Biology of Acute and Chronic Traumatic Encephalopathies, which will share opening keynote addresses and a fourth day of sessions with this meeting.
 Sujets Keystone Symposia, ApoE, Alzheimer's, Lipoprotein Biology, Neurodegenerative Disease, Neurobiology, Signaling, Signalling
 Page web http://www.keystonesymposia.org/12Q5
 Sujets apparentés Biologie; Médecine (en général)
  
4.Keystone Symposia: Clinical and Molecular Biology of Acute and Chronic Traumatic Encephalopathies
 Dates 26 Fév 2012 → 02 Mar 2012
[ID=427838] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé Acute traumatic brain injury (TBI) and its long-term neurodegenerative complications (known collectively as chronic traumatic encephalopathy, or CTE) are increasingly recognized as major public health issues, especially in the context of sports-related head injury and battlefield blast (military) exposure. Awareness of these issues has risen as neurological, psychiatric and neurodegenerative phenomena are associated with professional athletes and with veterans returning from Iraqi and Afghan theaters. The physics of head injury, as well as the epidemiological and neuropsychiatric aspects of sports-related and blast-related syndromes, will be reviewed in the initial sessions of this three-day meeting. Advances in functional neuroimaging and in the rapid and convenient determination of peptides and proteins in the cerebrospinal fluid and plasma will be reviewed in terms of their possible pathobiological significance as well as their identities as possible biomarkers. Later sessions will focus on the overlap between CTE and major neurodegenerative diseases, such as Alzheimer?s Disease (AD), frontotemporal dementia and amyotrophic lateral sclerosis. CTE is associated with accumulation of aggregated proteins or protein fragments, including tau, TDP-43, the Alzheimer?s amyloid precursor protein (APP) and the APP metabolite, amyloid-b. New experimental therapeutics research targets the roles these abnormal protein structures play in injury severity and subsequent outcome. Ab-lowering medications, currently in clinical trials for AD, improve outcome following acute brain trauma in rodent models, suggesting a pathway toward potential therapeutic interventions. Because apolipoprotein E (APOE) isotype is an important determinant of outcome from acute severe as well as mild repetitive TBI, this meeting coincides in time and venue with the Keystone Symposia meeting on ApoE, Alzheimer?s and Lipoprotein Biology. Opening plenary sessions and an optional fourth day of sessions are available for those interested in learning more about basic biology and/or clinical interventions related to APOE.
 Sujets Keystone Symposia, Clinical and Molecular Biology, Acute and Chronic Traumatic Encephalopathies, Neurobiology
 Page web http://www.keystonesymposia.org/12Q6
 Sujets apparentés Neurologie; Médecine (en général)
  
5.Keystone Symposia: Protein-RNA Interactions in Biology and Disease
 Dates 04 Mar 2012 → 09 Mar 2012
[ID=427782] Haut de la page
 LieuSanta Fe, NM, États-Unis
 Résumé Cellular functions depend on numerous protein-coding and noncoding RNAs and the RNA-binding proteins (RBPs) associated with them, which form ribonucleoprotein complexes (RNPs). Mutations that disrupt either the RNA or protein components of RNPs or the factors required for their assembly can be deleterious. The discovery of disease-causing mutations in RNAs or their interacting RBPs not only adds to our growing understanding of RNA biology and chemistry, but also offers new therapeutic targets and contributes to ongoing efforts in developing mRNA-targeting antisense and RNAi therapeutics. This meeting focuses on a general understanding of post-transcriptional gene regulation and how perturbation of complex networks of RNA-protein and RNA-RNP interactions triggers disease.
 Sujets Keystone Symposia, Protein, Protein-RNA Interactions in Biology and Disease, Transcription, Translation, Expression, Molecular Biology, Signaling, Biochemistry, Cell Biology, Systems Biology, Genetics, Genomics, iRNA, Processing, Noncoding
 Page web http://www.keystonesymposia.org/12C1
 Sujets apparentés Biologie moléculaire; Médecine (en général)
  
6.Keystone Symposia: Innate Immunity: Sensing the Microbes and Damage Signals
 Dates 04 Mar 2012 → 09 Mar 2012
[ID=427836] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé In recent years there have been major advances in our understanding of the mechanisms that are involved in the recognition of microbes and subsequent activation of host immune defenses. Several classes of membrane-bound and cytosolic pattern recognition receptors (PRRs) have been identified and partially characterized. These include the Toll-like receptors (TLRs), NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs). Activation of PRRs leads to the production of a large array of pro-inflammatory and anti-microbial molecules that are critical for the elimination of invading pathogens and activation of adaptive immune responses. A class of cytosolic PRRs is involved in the assembly of the inflammasome, a molecular platform that mediates activation of caspase-1 and secretion of mature IL-1b and IL-18. Importantly, activation of the inflammasome is also induced by non-microbial mechanisms including endogenous molecules involved in the pathogenesis of metabolic and inflammatory diseases. In addition, there is evidence that autophagy, a cellular process that mediates recycling of intracellular components, is involved in microbial recognition and plays a key role in host defense. The initial sensing of microbes often occurs at mucosal surfaces, but the interplay between recognition of commensal vs. pathogenic microbes on the host immune system is only beginning to be uncovered. The goal of the Keystone Symposia meeting on Innate Immunity: Sensing the Microbes and Damage Signals is to gather scientists working on innate immunity to discuss cutting-edge research on the mechanisms that regulate the activation of the immune system by microbes as well as by endogenous damage signals, and to integrate such knowledge in the context of inflammation, homeostasis, host defense and disease. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on The Microbiome, which will share a keynote address and three plenary sessions with this meeting.
 Sujets Keystone Symposia, Innate Immunity, Sensing the Microbes and Damage Signals, Leukocytes, Immunology, Bacterial, Infectious Diseases, Viral, Signaling, Inflammation
 Page web http://www.keystonesymposia.org/12Q7
 Sujets apparentés Biologie; Médecine (en général)
  
7.Keystone Symposia: The Microbiome
 Dates 04 Mar 2012 → 09 Mar 2012
[ID=427835] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé Emerging themes from several traditionally disparate areas of research have begun to coalesce around the concept that the complex microbial communities that inhabit most external human surfaces play a key role in health and disease. Specifically, processes including basic immune system development, host-pathogen interactions, metabolic disease and cancer are all greatly influenced by the composition and bioactivity of the microbiota that live within us. Understanding how mammalian hosts regulate their microbiota and the myriad of ways by which the microbiota can alter susceptibility to a wide range of diseases is a key opportunity to better understand numerous diseases and, subsequently, provide strategies to promote human health. Thus, the goal of the Keystone Symposia meeting on The Microbiome is to facilitate the understanding of mechanisms that maintain a healthy host-microbiota relationship and explore how perturbations in this relationship increase susceptibility to a variety of diseases, especially those associated with chronic inflammation. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Innate Immunity: Sensing the Microbes and Damage Signals, which will share a keynote address and three plenary sessions with this meeting.
 Sujets Keystone Symposia, The Microbiome, Infectious Diesase
 Page web http://www.keystonesymposia.org/12Q8
 Sujets apparentés Médecine (en général); Biologie
  
8.Keystone Symposia: Nuclear Events in Plant Gene Expression and Signaling
 Dates 06 Mar 2012 → 11 Mar 2012
[ID=427867] Haut de la page
 LieuTaos, NM, États-Unis
 Résumé The complete sequences of a number of plant genomes and the advent of high-throughput technologies have, in the past few years, fueled intensive research efforts to unravel the mechanisms underlying gene and genome regulation. It is clear that a host of epigenetic processes including, but not limited to, DNA methylation and various histone modifications, underlie key developmental processes as well as biotic and abiotic interactions. Non-coding RNAs have been increasingly recognized as players in gene expression and genome defense. Various types of subcellular bodies in the nucleus have been identified and associated with transcription factors, RNA processing proteins and epigenetic regulators. Despite these advances, a holistic view of gene and genome regulation at the DNA, RNA, protein, cell biological and developmental levels is still lacking. By bringing together researchers working on various aspects of genome dynamics and gene expression, this symposium on Nuclear Events in Plant Gene Expression and Signaling aims to stimulate the synthesis of an integrative view of nuclear dynamics in plant biology.
 Sujets Keystone Symposia, Nuclear Events in Plant Gene Expression and Signaling, Plant Biology
 Page web http://www.keystonesymposia.org/12C2
 Sujets apparentés Biologie; Médecine (en général)
  
9.Keystone Symposia: Regulation of Lymphocyte Signaling
 Dates 11 Mar 2012 → 16 Mar 2012
[ID=427876] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé Key individual components of signaling pathways that control lymphocyte activation have been identified. However, their specific regulation, integration within pathways and regulation are still the subject of intense investigation. Currently, they are being probed through biochemical, chemical-genetic, modeling and imaging methods. Major hurdles still reflect our very simplistic understanding of both the kinetic parameters of the molecules involved as well as the complexity of the regulatory circuits of these signaling pathways. Moreover, it is still quite difficult to translate such information into downstream biologically important information. The fact that therapeutics targeting these signaling pathways are still lagging is not surprising. The Keystone Symposia meeting on Regulation of Lymphocyte Signaling will highlight different methodologies and approaches aimed at developing a better integration of complex information about signaling. This information will lead to better understanding of how the normal immune system functions and where interventions in signaling pathways can be used in diseases of the immune system.
 Sujets Keystone Symposia, Regulation of Lymphocyte Signaling, Immunology
 Page web http://www.keystonesymposia.org/12C4
 Sujets apparentés Biologie; Médecine (en général)
  
10.Keystone Symposia: Mutations, Malignancy and Memory ? Antibodies and Immunity
 Dates 18 Mar 2012 → 22 Mar 2012
[ID=427885] Haut de la page
 LieuBoston, MA, États-Unis
 Résumé Mutations in the human genome are regarded as potentially disastrous events that lead to carcinogenesis. From the vantage point of B cell immunology, however, programmed DNA alterations at the antibody gene loci are essential for efficient antibody responses. A plethora of recent findings are beginning to illuminate open questions about the precise molecular mechanisms of these diversification processes, their regulation, and how errors in these pathways lead to cancer. Furthermore, the very same class of mutator enzymes plays an underappreciated role in non-lymphoid cancers, in antiviral responses and in epigenetic reprogramming. Antibody diversification not only shapes the repertoires of the immunological memory, but also those of auto-antibodies. The Keystone Symposia meeting on Mutations, Malignancy and Memory ? Antibodies and Immunity will provide both a platform to integrate these more or less isolated fields and an opportunity to identify interfaces that could be relevant for therapeutic approaches in malignancies and autoimmune diseases.
 Sujets Keystone Symposia, Mutations, Malignancy, Memory, Antibodies, Immunity, Cancer, B-Cell Biology, B Cell
 Page web http://www.keystonesymposia.org/12C6
 Sujets apparentés Médecine (en général)
  
11.Keystone Symposia: Addressing the Challenges of Drug Discovery ? Novel Targets, New Chemical Space and Emerging Approaches
 Dates 19 Mar 2012 → 23 Mar 2012
[ID=427915] Haut de la page
 LieuTahoe City, CA, États-Unis
 Résumé The scientific and organizational landscape that underpins drug discovery is in a state of rapid evolution. The cellular signal transduction processes and biochemical pathways that enable life are increasingly understood at the molecular level and hypotheses for disease intervention can be proposed within this rational context. Technology to enable discovery of ligands to perturb the function of biological targets continues to advance and new methods to create small molecule tools to interrogate biological processes and potentially serve as drug leads are under development. However, while industry investment in R&D has grown exponentially, approval of new medicines has remained constant for several decades. Juxtaposition of this scientific opportunity, the continuing societal need for new drugs, and a failing model for translation of basic research into new medicines provides fertile soil for new ideas and approaches. This meeting will focus on addressing these challenges in drug discovery with an emphasis on novel biological targets, new chemical space and emerging organizational approaches to more effective translation. The goals of the meeting are: ? To explore relatively uncharted protein target class families to define new druggable biological space ? To survey promising new chemical approaches for ligand discovery ? To highlight new organizational constructs for drug discovery with an emphasis on public/private partnerships The meeting aims to bring together medicinal chemists, disease biologists, chemical biologists, assay developers, and screeners from industry and academics, along with leaders of R&D organizations to create a dynamic exchange around the challenges facing drug discovery.
 Sujets Keystone Symposia, Challenges, Drug Discovery, Novel Targets, New Chemical Space, Emerging Approaches, Diagnostics
 Page web http://www.keystonesymposia.org/12F1
 Sujets apparentés Pharmacologie et développement des médicaments; Médecine (en général)
  
12.Keystone Symposia: HIV Vaccines
 Dates 21 Mar 2012 → 26 Mar 2012
[ID=427912] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé The 2012 Keystone Symposia meeting on HIV Vaccines will focus on basic aspects of immunology and HIV-1 virology to highlight issues that challenge the field. The genetic diversity of circulating HIV-1 variants puts extreme demands on the quality of the response a prophylactic vaccine will need to elicit. Most likely, conserved viral determinants need to be targeted and the response must be sustained over time. To facilitate a broad and open discussion around these topics, the symposium will convene expert investigators from the HIV-1 vaccine field as well as a number of basic immunologists. Aspects of natural HIV-1 infection of direct relevance to the development of a vaccine, such as viral transmission and viral escape from immune responses, will be addressed in joint sessions with the parallel meeting on Viral Immunity and Host Gene Influence. Speakers will also be invited to present in the workshops and in the oral sessions based on submitted abstracts.
 Sujets Keystone Symposia, HIV, vaccines, immunology, infectious diseases, viral, cell, biology, b-cell, t-cell
 Page web http://www.keystonesymposia.org/12X5
 Sujets apparentés Médecine (en général); Biologie
  
13.Keystone Symposia: Viral Immunity and Host Gene Influence
 Dates 21 Mar 2012 → 26 Mar 2012
[ID=427999] Haut de la page
 LieuKeystone, CO, États-Unis
 Résumé This meeting will focus on recent advances in viral immunity and host gene influence that have most excited the scientific community. Systems biology approaches are being increasingly applied to the exploration of host-pathogen interactions, including the impact of viral infection on innate and adaptive immunity. Accordingly, the keynote talk will be on this topic. The first full session on the next day will focus on innate immunity, a field that continues to evolve rapidly and hold great interest in the field. In the evening the audience will hear from others who have successfully applied a systems biology approach to examine virus-host interactions. The second day explores adaptive immunity, a topic that historically has been a centerpiece for this meeting, and an area that continues to move forward rapidly. On the third day, the morning session will focus on immune evasion and subversion and will illustrate how formidable the opposition can be and why vaccine development for a number of important human diseases is so challenging. Talks on persistent and chronic viral infections, a topic with clear relevance to a number of human diseases, will be covered in the evening session. The morning session of the final day will cover immune tailoring in non-lymphoid tissues; talks will illustrate how different host responses can and must be, depending upon anatomical location of the infection. The final session will cover the latest advances in the development of vaccines and therapeutics, the traditional ending for this meeting series and a reminder to attendees of the ultimate objectives. Overall, the objective of the Keystone Symposia meeting on Viral Immunity and Host Gene Influence is to accelerate progress in understanding and manipulating anti-viral immunity to improve human health. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on HIV Vaccines, which will share a keynote address and three plenary sessions with this meeting. We anticipate this pairing will facilitate a wider cross-fertilization of ideas and foster innovative collaborations among scientists working in vaccinology and those studying innate immune mechanisms and other viral diseases.
 Sujets Keystone Symposia, Viral, Immunity, Host, Gene, Influence, immune mechanisms, immunology, infectious diseases, systems, biology, cell, antibodies, innate, immunity, t-cell,
 Page web http://www.keystonesymposia.org/12X6
 Sujets apparentés Médecine (en général); Biologie
  
14.Biochemical Journal - US Symposium
 Date de début22 Mar 2012
[ID=448042] Haut de la page
 LieuLa Jolla, CA, États-Unis
 Résumé In gratitude to the Sanford-Burnham Medical Research Institute for hosting its US Editorial Office, the Biochemical Journal is sponsoring a special one-day symposium on Thursday March 22nd 2012. Registration for this event is free.
 Page web http://www.biochemj.org/bj/symposium/
  
15.Keystone Symposia: Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics
 Dates 30 Mar 2012 → 04 Avr 2012
[ID=427972] Haut de la page
 LieuBig Sky, MT, États-Unis
 Résumé Fibrosis is a pathological process in which diseased tissue is replaced with excess extracellular matrix ultimately leading to organ scarring and failure, a final common pathway in many forms of chronic disease affecting multiple tissues. Currently, there are minimal and inadequate treatment options for fibrotic disease. The field of fibrosis is emerging and there is a strong need to understand the cellular, molecular and genetic basis of fibrosis in humans and to develop animal models that reproduce and dissect this pathological process. There is also a need to identify prognostic markers of disease susceptibility, biomarkers of disease progression and improved technologies to monitor the effectiveness of new therapies. The goal of the Keystone Symposia meeting on Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics is to bring together researchers and clinicians in academia and industry to provide an integrated perspective of basic disease mechanisms, the more pragmatic challenges associated with executing clinical trials and approaches to improve clinical development of anti-fibrotic drugs.
 Sujets Fibrosis, Disease, Novel, Therapeutics, Keystone Symposia, inflammation, immunity, innate, immunology, signaling, biochemistry, basic mechanisms, cancer, endothelium, cell, biology
 Page web http://www.keystonesymposia.org/12D1
 Sujets apparentés Médecine (en général); Biologie
  
16.Keystone Symposia: Non-Coding RNAs
 Dates 31 Mar 2012 → 05 Avr 2012
[ID=428004] Haut de la page
 LieuSnowbird, UT, États-Unis
 Résumé It has become apparent that RNA plays a major, but still largely unexplored, role in the regulation of gene expression. It is becoming increasingly evident that longer forms of non-protein-coding RNAs (ncRNAs) are involved directly in regulating gene expression and epigenetic states. These long ncRNAs appear to be functioning as an endogenous RNA regulatory system, playing a major role in the epigenetic control of differentiation and development. These observations, across various model systems, strongly suggest that long ncRNAs are more intricately involved in the regulation of gene expression than previously envisioned. The goal of the Keystone Symposia meeting on Non-Coding RNAs is to highlight the similarities and differences in various model systems to better understand the role of long ncRNAs in the regulation of genomes. This is an entirely new emerging field of study that is on the forefront of modern biology. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Eukaryotic Transcription, which will share a plenary session with this meeting.
 Sujets Keystone Symposia, Non-Coding, RNAs, RNA, genetics, genomics, molecular, biology, transcription, translation, expression, vertebrate, development, chromatin, structure, function, processing, noncoding
 Page web http://www.keystonesymposia.org/12Z1
 Sujets apparentés Biologie moléculaire; Médecine (en général)
  
17.Keystone Symposia: Synapses and Circuits: From Formation to Disease
 Dates 01 Avr 2012 → 06 Avr 2012
[ID=428024] Haut de la page
 LieuSteamboat Springs, CO, États-Unis
 Résumé A fundamental goal of neuroscience is to understand the molecular, cellular and activity-based mechanisms that control the formation and maintenance of neural circuits and determine how these mechanisms become compromised in neurodevelopmental, psychiatric and neurodegenerative disorders. Over the past two decades, molecular neuroscientists have identified key molecules and mechanisms that underlie synapse development, activity and stability. Meanwhile, the study of neuronal circuits has been revolutionized by new methods to visualize and map circuits in living animals, as well as the development of approaches to control neuronal activity using optical approaches (so called optogenetics). Finally, disease researchers have identified genes associated with neurodevelopmental and psychiatric disorders and neurodegenerative diseases. Animal models of these diseases are proving useful to understand how dysfunction of affected genes and proteins contributes to disease pathology. Although these fields are working on the same processes, no small highly interactive meeting brings these three groups together. The Keystone Symposia meeting on Synapses and Circuits: From Formation to Disease will address this need by bringing together leaders working on synapse development and function, circuit structure and function and the study of brain disease. We anticipate that mutually beneficial insights will emerge from discussions at this meeting.
 Sujets neural, circuits, neurodevelopmental, psychiatric, neurodegenerative, disorders, disease, development, neurobiology, neurophysiology, signaling, Keystone Symposia, synapses, circuits
 Page web http://www.keystonesymposia.org/12D2
 Sujets apparentés Médecine (en général)
  
18.Keystone Symposia: Regenerative Tissue Engineering and Transplantation
 Dates 01 Avr 2012 → 06 Avr 2012
[ID=428089] Haut de la page
 LieuBreckenridge, CO, États-Unis
 Résumé Tissue engineering and regenerative medicine is a dynamic, translational research field that amalgamates life sciences, engineering and clinical medicine for the purpose of restoring structure and function to diseased, damaged or injured tissues and organs. Current efforts focus on the application of stem and progenitor cells, bioactive factors and biomaterial scaffolds in transplantation procedures to affect regenerative therapies. Breakthroughs in bladder and tracheal reconstruction and highly promising approaches for solid organ regeneration as well as musculoskeletal and nerve repair have been achieved. Effective cell sourcing, optimal assembly and fabrication of tissue-derived and synthetic biomaterial scaffolds, and targeted regulation of therapeutic and immunomodulatory functions of stem cells represent some of the current challenges in this field. In this Keystone Symposia meeting on Regenerative Tissue Engineering and Transplantation, exciting technological and intellectual advances in the field will be synthesized by expert scientists, engineers and clinicians to assess and expand the landscape in regenerative engineering and transplantation. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Mechanisms of Whole Organ Regeneration, which will share an opening and closing keynote address as well as two plenary sessions with this meeting. More specifically, the pairing of these two meetings represents a highly unusual opportunity for cross-talk between the more applications-driven field of tissue engineering and regenerative medicine, and the very basic research being explored in the field of whole organ regeneration.
 Sujets Keystone Symposia, Regenerative, Tissue, Engineering, Transplantation, organ systems, development, regenerative, technologies, transplantation
 Page web http://www.keystonesymposia.org/12Z3
 Sujets apparentés Médecine (en général)
  
19.Keystone Symposia: Mechanisms of Whole Organ Regeneration
 Dates 01 Avr 2012 → 06 Avr 2012
[ID=428033] Haut de la page
 LieuBreckenridge, CO, États-Unis
 Résumé The regeneration of organs and organ systems after injury is widely, but unevenly, distributed among animals. Why organ regeneration is not shared by all animals, and whether mechanisms may or may not be conserved among those animals that can regenerate remain open questions. In recent years, the use of a wider range of model organisms and an increasing ability to use genetic tools to study regeneration has spurred significant progress in our understanding of animal regenerative biology. This meeting aims to delineate the molecular and cellular biological basis of regeneration by highlighting, comparing and contrasting the differences and similarities in regenerative capabilities and mechanisms among diverse animal species. How these biological findings may inform regenerative medicine and stem-cell biology and therapeutics will be considered and discussed. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Regenerative Tissue Engineering and Transplantation, which will share an opening and closing keynote address as well as two plenary sessions with this meeting.
 Sujets Keystone Symposia, Mechanisms, Organ, Regeneration, development, stem cells, genomics, systems, genetics, aging, cell, biology, morphogenesis
 Page web http://www.keystonesymposia.org/12Z4
 Sujets apparentés Biologie; Médecine (en général)
  
20.Ninth International 'RNAi: MicroRNAs & Oligos-Boston-2012 Meeting' On 'RNA interference & MicroRNAs: Biochemistry to Drugs & Therapeutics
 Dates 01 Mai 2012 → 02 Mai 2012
[ID=462227] Haut de la page
 LieuWaltham, États-Unis
 Sujets The Genetics of RNAi and microRNAs, RNAi, Oligos delivery in vivo, in vitro, microRNAs and their diverse roles in biology & disease, Computational and Disease Biology of miRNAs, Chemical synthesis of peptides and oligos, Large scale manufacturing and process development, Drug Target identification and Validation, High throughput genome-wide screenings, Development of Oligos and Peptide as Therapeuti, Clinical Application of Oligos and Peptides
 Page web http://www.expressgenes.com
 Contact Tél.: [7818918181]; Email.: sham@expressgenes.com
 Sujets apparentés Biologie
  
21.Third International 'Frontiers in Synthetic Biology, Biofuels & Green Chemistry-2012- Meeting' On 'Synthetic Genomes to Biofuels & Renewable Clean Energy Production'
 Dates 01 Mai 2012 → 02 Mai 2012
[ID=462246] Haut de la page
 LieuWaltham, États-Unis
 Sujets Synthetic Genomics & Organelle Synthesis,
 Page web http://www.expressgenes.com
 Contact PO Box 540179 Waltham, MA 02451 USA; Tél.: [7818918181]; Email.: sham@expressgenes.com
 Sujets apparentés Biotechnologie
  
22.LIPID MAPS Meeting 2012 — LIPID MAPS Annual Meeting 2012: Impact on Cell Biology, Metabolomics and Translational Medicine
 Dates 07 Mai 2012 → 08 Mai 2012
[ID=444241] Haut de la page
 LieuLa Jolla, California, États-Unis
 Résumé This is an exciting time for the emerging field of lipidomics. With the development and evolution of sophisticated mass spectrometers linked to highly efficient liquid chromatography systems, individual molecular species of lipids can now be isolated and identified, allowing us to begin to understand lipid metabolism and the treatment of lipid-based diseases (atherosclerosis and inflammatory disease as well as arthritis, cancer, diabetes and Alzheimer's disease). Recent awareness that each category of lipid consists of thousands if not tens of thousands of individual molecular species requires sophisticated informatics to ensure consistent databasing and annotation of the numerous lipid molecular species and analysis of tremendous quantities of experimental data. The goal of this meeting is to bring together biological and biomedical scientists in a wide range of fields to share new findings and methods in the broader lipidomics field and to explore joint efforts to extend the use of these powerful new methods to new applications. Presentations will provide an excellent introduction for scientists new to these methods, and are sure to be of interest to lipidomics veterans to learn about latest techniques and research results.
 Sujets Cancer, Inflammation, Macrophage Biology, Metabolic Disease, Metabolomics, Translational Medicine
 Page web http://www.lipidmaps.org/meetings/2012annual/index.html
 Contact Tél.: (858-822-5853); Email.: mdisenhouse@ucsd.edu
 Sujets apparentés Bio-informatique; Spectroscopie de masse et résonance magnétique nucléaire
  
23.NMCS — ACS 2012 National Medicinal Chemistry Symposium
 Dates 20 Mai 2012 → 23 Mai 2012
[ID=461935] Haut de la page
 LieuTucson, États-Unis
 Résumé The 33rd National Medicinal Chemistry Symposium will be held from May 20-23rd, 2012 at the Hilton El Conquistador Resort in Oro Valley, AZ. Participants will represent both industry and academia and will include scientists ranging from graduate students to the most accomplished leaders in the field. We hope that you can join us in May 2012 for this exciting program at the grand El Conquistador Resort.
 Sujets medicinal chemistry, natural products, anti-infectives, neurodegeneration, chromatin, autoimmune, inflammatory, allosteric modulators, molecular libraries, graduate student, career development workshop
 Page web http://medchemconf.pharmacy.arizona.edu/index.html
 Contact Nicole Schechter 1580 East Hanley Blvd Oro Valley, AZ 85737; Tél.: [5206268222]; Email.: schechter@pharmacy.arizona.edu
 Sujets apparentés Chimie analytique; Foire exposition chimie
  
24.Biopolymers
 Dates 03 Jui 2012 → 08 Jui 2012
[ID=454752] Haut de la page
 LieuNewport, RI, États-Unis
 Organisateur Gordon Research Conferences
 Résumé The 2012 Biopolymers Gordon Research Conference will explore recent advances and future trends in understanding the relationship between structure and function of biological polymers (e.g. proteins, nucleic acids, macromolecular assemblies), with emphasis on physical and chemical principles underlying their behaviors in solution and in the cellular environment. Session topics will span multiple disciplines, including the consequences of macromolecular crowding, the mechanisms of macromolecular complex assembly and aggregation, structural dynamics and allostery, elasticity and mechanics, and protein folding and design. The sessions have been organized so that each topic is addressed using diverse approaches and techniques including simulation, spectroscopy, single molecule measurements, x-ray crystallography and a variety of biochemical and biophysical solution methods, with applications to basic and clinical science. The Biopolymers GRC is uniquely poised to foster multidisciplinary and interdisciplinary connections between chemistry, computer science, physics and biology. This meeting of scientists applying experimental and theoretical methods to study biological polymers encourages the exchange and discussion of results and ideas among participants with different backgrounds, thereby promoting interdisciplinary research activities.

We encourage early registration and submission of abstracts for the poster session. We plan to select posters for short presentations for most of the meeting sessions.

 Page web http://www.grc.org/programs.aspx?year=2012&program=biopolym
 Sujets apparentés Chimie organique et polymères
  
25.Bioorganic Chemistry
 Dates 10 Jui 2012 → 15 Jui 2012
[ID=454820] Haut de la page
 LieuAndover, NH, États-Unis
 Organisateur Gordon Research Conferences
 Résumé The Gordon Research Conference on Bioorganic Chemistry was founded in 1992 to bring together scientists from a range of disciplines to present and discuss cutting-edge research at the interface between chemistry and biology. Both fundamental and applied research relevant to academia and industry are highlighted. To maintain a balance between these areas, the conference is organized by two co-chairs, one from academia and one from industry. The conference emphasizes the presentation of techniques or approaches that are broadly applicable across multiple areas of chemical and biological research. Traditionally, small molecules that probe, modulate, or mimic cellular components or processes as well as studies of biology at the molecular level have been of particular interest.
 Page web http://www.grc.org/programs.aspx?year=2012&program=bioorg
  
26.Metals in Medicine
 Dates 24 Jui 2012 → 29 Jui 2012
[ID=455183] Haut de la page
 LieuAndover, NH, États-Unis
 Organisateur Gordon Research Conferences
 Résumé The 2012 Gordon Conference on Metals in Medicine will present cutting-edge research on complexes of various metal ion complexes as drugs, as enzyme inhibitors and as imaging probes. The Conference will feature a wide range of topics including advances in platinum and other metal complexes as anti-cancer drugs, iron biochemistry, copper and zinc in physiology and disease, radionuclides in imaging and therapy, metalloproteins as medicinal targets, and metal ions in imaging from cells to animals to humans. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promote cross-disciplinary collaborations in the various research areas represented.
 Page web http://www.grc.org/programs.aspx?year=2012&program=metalsmed
 Sujets apparentés Physique appliquée: Biophysique; Pharmacologie et développement des médicaments
  
27.Biocatalysis
 Dates 08 Jul 2012 → 13 Jul 2012
[ID=455296] Haut de la page
 LieuSmithfield, RI, États-Unis
 Organisateur Gordon Research Conferences
 Résumé Biocatalysis encompasses the use of enzymes or whole cell systems for effecting the conversion of readily available, inexpensive starting materials to high value products. Enzymes are fully recyclable catalytic proteins that frequently display exquisite chemo-, enantio- and regioselectivity and operate under mild conditions of pH and temperature. These characteristics make them cost effective and sustainable catalysts for a wide range of chemical transformations. Modern tools of protein discovery, design and engineering aid the development of novel biocatalysts and their tailor-designed integration into industrial processes. Consequently, they find wide application in the production of pharmaceutical intermediates, novel materials and diagnostics,as well as fine, performance and agrochemicals. The Biocatalysis Gordon Conference highlights the best science, technologies and case studies responsible for the understanding, development and practical use of biocatalysts around the world.
 Page web http://www.grc.org/programs.aspx?year=2012&program=biocat
 Sujets apparentés Catalyse
  
28.PREP2012 — 25th International Symposium, Exhibit and Workshops on Preparative and Process Chromatography
 Dates 15 Jul 2012 → 18 Jul 2012
[ID=450302] Haut de la page
 LieuBoston, États-Unis
 Résumé Outstanding program will be packed with papers on biochromatography, QbD, monoclonal antibodies, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, SMB, APIs, monoliths and new stationary phases, and more! 60+ oral presentations, 2-day Poster Session, 2½-day Exhibit, and workshops. The most recognized international meeting covering the latest developments in preparative and process liquid chromatography, separation science and technology, PREP2012.
 Sujets preparative chromatography, process chromatography, chromatographic separations, process liquid chromatography, fine chemicals, chiral molecules, active pharmaceutical ingredients, peptides, proteins, monoclonal antibodies, plasmids, vaccines, VLP?s, biopharmaceuticals
 Page web http://www.PREPsymposium.org
 Contact Janet Cunningham, ISSF 2012 Symposium/Exhibit Manager, Barr Enterprises; Email.: janetbarr@aol.com
 Sujets apparentés Formation en chromatographie (GC, HPLC, UPLC)
  
29.2012 AACC Annual Meeting
 Dates 15 Jul 2012 → 19 Jul 2012
[ID=432386] Haut de la page
 LieuLos Angeles, États-Unis
 Organisateur American Association for Clinical Chemistry
 Page web http://www.aacc.org/events/2012am/pages/default.aspx
  
30.Protein Cofactors, Radicals & Quinones
 Dates 29 Jul 2012 → 03 Aou 2012
[ID=455673] Haut de la page
 LieuSouth Hadley, MA, États-Unis
 Organisateur Gordon Research Conferences
 Résumé Many enzyme-catalyzed reactions are now known to require the assistance of complex cofactors that incorporate redox-active metal centers and organic molecules, including in many instances cofactors generated by post-translational modification of amino acid residues on the enzyme itself. The 2012 Protein Cofactors, Radicals, and Quinones Gordon Research Conference will bring together scientists who study the biogenesis and assembly of these complex cofactors, as well as the mechanisms of the catalytic chemistry carried out by these cofactors in the functioning enzymes. The conference will include reports of new research on aerobic and anaerobic radical enzymes, enzymes that utilize quinones and other cofactors derived via oxidation and crosslinking of amino acid residues, and the role of metal ions in both cofactor biogenesis and catalysis. This conference will bring together researchers from diverse disciplines including mechanistic enzymology, bioinorganic chemistry, bioorganic chemistry, spectroscopy, computational chemistry, and structural biology.

An important part of this Gordon Conference is the poster sessions, which provide opportunities to present and informally discuss your most recent results. All conferees are encouraged to participate by presenting a poster; several speakers will be invited to present short talks based on the submitted poster abstracts.

This Gordon Conference has a strong history of promoting participation by young scientists, including graduate students, postdoctoral associates, and assistant professors, and again for the 2012 conference we would especially like to encourage applications and poster abstract submissions by young scientists.

 Page web http://www.grc.org/programs.aspx?year=2012&program=protcofac
  
31.Medicinal Chemistry
 Dates 05 Aou 2012 → 10 Aou 2012
[ID=455741] Haut de la page
 LieuNew London, NH, États-Unis
 Organisateur Gordon Research Conferences
 Page web http://www.grc.org/programs.aspx?year=2012&program=medchem
  
32.Biomineralization
 Dates 12 Aou 2012 → 17 Aou 2012
[ID=455863] Haut de la page
 LieuNew London, NH, États-Unis
 Organisateur Gordon Research Conferences
 Résumé The Gordon Research Conference on Biomineralization is exploring the basic principles by which organisms synthesize, control and make use of minerals, as well as potential applications of these. Spectacular advances have been made in the last years and are impacting various scientific fields, from biology to geology, from medicine to materials science and from evolutionary sciences to engineering. The central goal of this GRC is to create a stimulating environment for scientists from all these disciplines to discuss latest ideas and recent advances on how minerals interact with biomolecules, on how cellularly driven biomineralization is regulated by extracellular matrix molecules, on how the structures of mineralized tissues relate to their function and on how these principles might influence our thinking in materials science and engineering. The conference will cover all kinds of biominerals, including carbonates, phosphates, oxides and silica, in vertebrates, invertebrates and plants. It will also address human health issues related to abnormal mineralization or diseases connected to mineral growth and homeostasis in the skeleton or in teeth.

The great success which this GRC experienced in the last years is largely due to its lively afternoon poster sessions, complementing the invited lectures. This provides the best opportunity to present latest research and exchange ideas in a more informal setting and all conferees are encouraged to submit and present posters. As done in previous conferences, 8-10 poster contributions will be selected for short oral presentations. All this has made this GRC very attractive for young scientists and - as the consequence of a vote in 2010 - the GRC on bimineralization 2012 will be complemented for the first time by a Gordon Research Seminar preceding the meeting.

 Page web http://www.grc.org/programs.aspx?year=2012&program=biomin
  

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Dernière mise à jour: 18 janvier 2012